PDS5B: PDS5 cohesin associated factor B
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5hdt chain A
5hdt chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S568 KQLEVLVS PTCSCKQ 1 9 - - - - - - - - - - - - - - - - - - 7 2 S1087 STTYSLES PKDPVLP 6 167 6 - 8 8 - - - - 6 4 35 34 17 15 - - - - 32 2 S1118 YLPPEMKS FFTPGKP 1 9 - - - - - - - - - - 5 4 - - - - - - - - T1121 PEMKSFFT PGKPKTT 6 226 74 - - - 6 3 54 - 37 22 - - - - 14 3 - - 4 9 S1139 GAVNKPLS SAGKQSQ 4 62 21 - 4 4 - - - - - - - - 12 12 7 2 - - - - S1140 AVNKPLSS AGKQSQT 4 97 17 - - - - - - - - - 15 14 4 4 35 8 - - - - S1159 METVSNAS SSSNPSS 3 34 9 - 12 4 - - 9 - - - - - - - - - - - - - S1160 ETVSNASS SSNPSSP 6 55 6 - 4 4 3 6 10 - - - - - 5 4 - - - - 11 2 S1161 TVSNASSS SNPSSPG 6 111 17 - 11 11 - - 10 - - - 20 20 5 4 - - - - 11 2 S1162 VSNASSSS NPSSPGR 10 598 38 - 41 30 39 32 45 - 12 7 53 49 32 29 25 7 41 17 83 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S568 KQLEVLVS PTCSCKQ - - - - - - - - - - - S1087 STTYSLES PKDPVLP -2.3e-4 - - - - - -2.3e-4 - - - - S1118 YLPPEMKS FFTPGKP - - - - - - - - - - - T1121 PEMKSFFT PGKPKTT 3.5e-3 - - - - 3.5e-3 - - - - - S1139 GAVNKPLS SAGKQSQ - - - - - - - - - - - S1140 AVNKPLSS AGKQSQT - - - - - - - - - - - S1159 METVSNAS SSSNPSS - - - - - - - - - - - S1160 ETVSNASS SSNPSSP - - - - - - - - - - - S1161 TVSNASSS SNPSSPG 0.023 - - - - - 0.023 - - - - S1162 VSNASSSS NPSSPGR 0.07 - -1.2e-3 0.84 - - 3.6e-7 3.5e-4 - -0.081 0.59
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S568
S1087
S1118
T1121
S1139
S1140
S1159
S1160
S1161
S1162
S1165
S1166
S1176
S1177
S1182
Y1187
T1188
S1190
S1191
T1220
T1223
S1246
T1255
S1257
S1259
S1283
T1301
S1319
S1334
S1358
S1362
S1366
T1367
S1369
T1370
S1379
T1381
S1383
S1406
S1407
S1416
S1417
T1427
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation CCRCC S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation COAD S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation GBM S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation HNSCC S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation LSCC S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation LUAD S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation OV S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation PDAC S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation UCEC S568 S1087 S1118 T1121 S1139 S1140 S1159 S1160 S1161 S1162 S1165 S1166 S1176 S1177 S1182 Y1187 T1188 S1190 S1191 T1220 T1223 S1246 T1255 S1257 S1259 S1283 T1301 S1319 S1334 S1358 S1362 S1366 T1367 S1369 T1370 S1379 T1381 S1383 S1406 S1407 S1416 S1417 T1427 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S568
S1087
S1118
T1121
S1139
S1140
S1159
S1160
S1161
S1162
S1165
S1166
S1176
S1177
S1182
Y1187
T1188
S1190
S1191
T1220
T1223
S1246
T1255
S1257
S1259
S1283
T1301
S1319
S1334
S1358
S1362
S1366
T1367
S1369
T1370
S1379
T1381
S1383
S1406
S1407
S1416
S1417
T1427
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S568
S1087
S1118
T1121
S1139
S1140
S1159
S1160
S1161
S1162
S1165
S1166
S1176
S1177
S1182
Y1187
T1188
S1190
S1191
T1220
T1223
S1246
T1255
S1257
S1259
S1283
T1301
S1319
S1334
S1358
S1362
S1366
T1367
S1369
T1370
S1379
T1381
S1383
S1406
S1407
S1416
S1417
T1427
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.