Protein: ENSP00000314505
Gene: MCM9

LinkedOmicsKB © 2022-2023 Zhang Lab

MCM9:
minichromosome maintenance 9 homologous recombination repair factor

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S297DFWEYYKSDPFAGRN17------------43------
S663QNQSVHQSQPRVLEV188-------------------
S711PGGSPEGSPVLDPPP19--------63----------
S762PKNTVVVSPHPKTSG852256-2323----71431096660421030115315
S802VDIGLLPSPGETGVP4121--1111------3936--52--611
S883PQSTPVHSPDRMLDS462--------1611559871----
S915ENVKPPGSPVAKLAK101013122-5141362764-45261039410193481247196816
S952ATKIAVHSPKISQRR517043---------252343268--344
S1071TPPSESKSKSPPPER15----------------32--
S1073PSESKSKSPPPERKN629915-----44---6358--26733162512
Showing 1 to 10 of 13 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S297DFWEYYKSDPFAGRN-----------
S663QNQSVHQSQPRVLEV-----------
S711PGGSPEGSPVLDPPP-----------
S762PKNTVVVSPHPKTSG7.8e-7-0.47--2.6e-7-2.3e-60.018-7.1e-30.067
S802VDIGLLPSPGETGVP-0.091------0.091----
S883PQSTPVHSPDRMLDS-----------
S915ENVKPPGSPVAKLAK5e-13-6.1e-40.24--0.811.3e-221.3e-59.2e-3-0.0610.23
S952ATKIAVHSPKISQRR2.9e-12-----2.9e-12----
S1071TPPSESKSKSPPPER-----------
S1073PSESKSKSPPPERKN0.33-----1.6e-15---2.8e-5-0.035
Showing 1 to 10 of 13 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationCCRCCS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationCOADS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationGBMS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationHNSCCS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationLSCCS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationLUADS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationOVS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationPDACS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylationUCECS297S663S711S762S802S883S915S952S1071S1073S1088S1103S1109proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.