DNMBP: dynamin binding protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ug1 chain A
1uhc chain A
4cc2 chain A
4cc2 chain C
4cc3 chain A
4cc3 chain C
4cc3 chain E
4cc3 chain G
4cc4 chain B
4cc4 chain D
4cc4 chain F
4cc7 chain A
4cc7 chain C
4cc7 chain E
4cc7 chain G
4cc7 chain I
4cc7 chain K
4cc7 chain M
4glm chain A
4glm chain B
4glm chain C
4glm chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S135 SQSRQWHS QSALFQI 4 51 - - - - - - 9 - 5 3 9 9 9 7 - - - - - - S137 SRQWHSQS ALFQIPE 1 9 - - - - 6 3 - - - - - - - - - - - - - - S284 EDGWLEGS LKGRTGI 3 58 - - 3 3 - - 18 - - - - - 17 17 - - - - - - S316 MALPQEGS LARIPET 1 6 - - - - - - - - - - - - - - - - - - 6 - T323 SLARIPET SLDCLEN 1 8 - - - - - - - - - - - - - - - - 6 2 - - S324 LARIPETS LDCLENT 9 521 39 - 4 4 5 4 36 - 70 39 54 50 76 69 - - 28 12 27 4 S342 EEQRHETS DHEAEEP 3 52 - - - - - - 17 - 12 6 9 8 - - - - - - - - S354 EEPDCIIS EAPTSPL 2 35 - - - - - - - - 12 6 9 8 - - - - - - - - S359 IISEAPTS PLGHLTS 1 17 - - - - - - 17 - - - - - - - - - - - - - S387 TAGGPPRS PGVEWEM 4 42 17 - - - - - - - - - 5 4 - - 8 - - - 6 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S135 SQSRQWHS QSALFQI - - - - - - - - - - - S137 SRQWHSQS ALFQIPE - - - - - - - - - - - S284 EDGWLEGS LKGRTGI - - - - - - - - - - - S316 MALPQEGS LARIPET - - - - - - - - - - - T323 SLARIPET SLDCLEN - - - - - - - - - - - S324 LARIPETS LDCLENT -4.5e-6 - - - - -9.2e-5 -0.22 -0.67 - -2.9e-4 - S342 EEQRHETS DHEAEEP - - - - - - - - - - - S354 EEPDCIIS EAPTSPL - - - - - - - - - - - S359 IISEAPTS PLGHLTS - - - - - - - - - - - S387 TAGGPPRS PGVEWEM - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S135
S137
S284
S316
T323
S324
S342
S354
S359
S387
S458
S483
S496
S578
T617
S659
S684
S689
S744
S996
S1005
S1258
S1268
S1351
S1353
S1371
S1379
S1381
T1384
S1407
S1419
S1436
S1486
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation CCRCC S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation COAD S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation GBM S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation HNSCC S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation LSCC S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation LUAD S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation OV S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation PDAC S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation UCEC S135 S137 S284 S316 T323 S324 S342 S354 S359 S387 S458 S483 S496 S578 T617 S659 S684 S689 S744 S996 S1005 S1258 S1268 S1351 S1353 S1371 S1379 S1381 T1384 S1407 S1419 S1436 S1486 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S135
S137
S284
S316
T323
S324
S342
S354
S359
S387
S458
S483
S496
S578
T617
S659
S684
S689
S744
S996
S1005
S1258
S1268
S1351
S1353
S1371
S1379
S1381
T1384
S1407
S1419
S1436
S1486
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S135
S137
S284
S316
T323
S324
S342
S354
S359
S387
S458
S483
S496
S578
T617
S659
S684
S689
S744
S996
S1005
S1258
S1268
S1351
S1353
S1371
S1379
S1381
T1384
S1407
S1419
S1436
S1486
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.