SSH1: slingshot protein phosphatase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S9 ALVTLQRS PTPSAAS 2 17 - - - - - - - - - - 5 5 4 3 - - - - - - T11 VTLQRSPT PSAASSS 1 10 - - - - - - - - - - 5 5 - - - - - - - - S57 LFLQQGSS PQGQRSL 1 9 - - - - - - - - - - - - - - - - - - 7 2 S63 SSPQGQRS LQHPHKH 1 18 - - - - - - - - - - - - 10 8 - - - - - - S261 LIKAKLRS IMMSQDL 4 91 - - 4 4 - - - - 17 11 14 14 - - - - 19 8 - - S441 AGFMRQLS EYEGILD 10 1029 70 - 57 47 40 23 81 - 52 30 83 76 106 97 12 4 102 40 91 18 Y443 FMRQLSEY EGILDAS 1 8 - - - - - - - - - - - - 4 4 - - - - - - S515 PCCFRRLS DPLLPSP 10 844 54 - 13 12 45 52 98 - 72 42 72 63 89 82 54 12 30 14 29 11 S521 LSDPLLPS PEDETGS 9 234 8 - 4 4 16 11 37 - 7 3 20 18 19 16 43 10 - - 7 11 S576 KKKLEFGS PKGRSGS 10 1406 122 - 99 76 69 66 90 - 102 59 108 99 102 93 48 11 105 44 95 18
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S9 ALVTLQRS PTPSAAS - - - - - - - - - - - T11 VTLQRSPT PSAASSS - - - - - - - - - - - S57 LFLQQGSS PQGQRSL - - - - - - - - - - - S63 SSPQGQRS LQHPHKH - - - - - - - - - - - S261 LIKAKLRS IMMSQDL - - - - - - - - - - - S441 AGFMRQLS EYEGILD 5e-26 - 0.58 0.41 - 1.6e-3 9.5e-8 2.8e-16 - 5.2e-15 0.04 Y443 FMRQLSEY EGILDAS - - - - - - - - - - - S515 PCCFRRLS DPLLPSP -6.8e-5 - - -4.8e-4 - -0.014 -0.13 0.86 -0.42 -0.83 -0.025 S521 LSDPLLPS PEDETGS 0.52 - - - - - 0.072 - -0.37 - - S576 KKKLEFGS PKGRSGS 5.4e-4 - 1.4e-7 4.0e-6 - 1.5e-9 -1.4e-4 -1.5e-3 0.28 3.4e-4 -1.4e-4
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S9
T11
S57
S63
S261
S441
Y443
S515
S521
S576
S581
S583
T590
S625
S778
S812
S834
S889
S894
S897
S909
S910
T922
S937
S938
S940
T955
S971
S988
T989
S1042
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation CCRCC S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation COAD S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation GBM S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation HNSCC S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation LSCC S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation LUAD S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation OV S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation PDAC S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation UCEC S9 T11 S57 S63 S261 S441 Y443 S515 S521 S576 S581 S583 T590 S625 S778 S812 S834 S889 S894 S897 S909 S910 T922 S937 S938 S940 T955 S971 S988 T989 S1042 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S9
T11
S57
S63
S261
S441
Y443
S515
S521
S576
S581
S583
T590
S625
S778
S812
S834
S889
S894
S897
S909
S910
T922
S937
S938
S940
T955
S971
S988
T989
S1042
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S9
T11
S57
S63
S261
S441
Y443
S515
S521
S576
S581
S583
T590
S625
S778
S812
S834
S889
S894
S897
S909
S910
T922
S937
S938
S940
T955
S971
S988
T989
S1042
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.