LCP1: lymphocyte cytosolic protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2d85 chain A
5joj chain A
5jol chain A
6vec chain a
6vec chain b
6vec chain c
6vec chain d
6vec chain e
6vec chain f
6vec chain g
6vec chain h
6vec chain i
6vec chain j
6vec chain k
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S5 ___MARGS VSDEEMM 10 1015 9 - 13 11 97 100 99 - 103 59 58 52 27 24 83 19 105 43 95 18 S7 _MARGSVS DEEMMEL 6 356 96 - 22 20 18 18 - - 11 6 55 52 29 29 - - - - - - Y28 VDTDGNGY ISFNELN 6 229 41 - 16 14 10 8 - - 19 9 50 46 8 8 - - - - - - S30 TDGNGYIS FNELNDL 3 69 - - 4 4 - - - - - - 14 13 18 16 - - - - - - T89 KSTDVAKT FRKAINK 1 3 - - - - - - - - - - - - - - - - 2 1 - - S107 ICAIGGTS EQSSVGT 2 19 - - - - - - - - 6 4 - - - - 8 1 - - - - S110 IGGTSEQS SVGTQHS 1 8 - - - - - - - - - - - - 4 4 - - - - - - S111 GGTSEQSS VGTQHSY 5 48 15 - - - - - - - 5 4 5 4 4 3 7 1 - - - - T114 SEQSSVGT QHSYSEE 5 129 30 - - - - - - - 11 8 24 23 9 7 - - - - 5 12 S117 SSVGTQHS YSEEEKY 2 23 - - - - - - - - - - - - - - 14 3 - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S5 ___MARGS VSDEEMM 0.19 - - 3.4e-6 - 1.9e-6 -3e-11 -6.2e-4 -6.9e-6 3.8e-7 3.7e-4 S7 _MARGSVS DEEMMEL -1.9e-3 - 5.1e-5 - - - -7.4e-9 -2.7e-4 - - - Y28 VDTDGNGY ISFNELN -3.2e-13 - - - - - -3.2e-13 - - - - S30 TDGNGYIS FNELNDL - - - - - - - - - - - T89 KSTDVAKT FRKAINK - - - - - - - - - - - S107 ICAIGGTS EQSSVGT - - - - - - - - - - - S110 IGGTSEQS SVGTQHS - - - - - - - - - - - S111 GGTSEQSS VGTQHSY - - - - - - - - - - - T114 SEQSSVGT QHSYSEE -0.013 - - - - - -0.013 - - - - S117 SSVGTQHS YSEEEKY - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S5
S7
Y28
S30
T89
S107
S110
S111
T114
S117
S257
S265
Y276
S290
T291
S323
T351
T353
Y374
S406
Y417
S474
S537
S539
S540
Y598
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation CCRCC S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation COAD S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation GBM S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation HNSCC S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation LSCC S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation LUAD S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation OV S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation PDAC S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation UCEC S5 S7 Y28 S30 T89 S107 S110 S111 T114 S117 S257 S265 Y276 S290 T291 S323 T351 T353 Y374 S406 Y417 S474 S537 S539 S540 Y598 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S5
S7
Y28
S30
T89
S107
S110
S111
T114
S117
S257
S265
Y276
S290
T291
S323
T351
T353
Y374
S406
Y417
S474
S537
S539
S540
Y598
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S5
S7
Y28
S30
T89
S107
S110
S111
T114
S117
S257
S265
Y276
S290
T291
S323
T351
T353
Y374
S406
Y417
S474
S537
S539
S540
Y598
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.