BAIAP2: BAR/IMD domain containing adaptor protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1wdz chain A
1wdz chain B
1y2o chain A
1y2o chain B
2ykt chain A
3rnj chain A
4js0 chain B
6bcr chain C
6bcr chain D
6bcr chain G
6bcr chain H
6bcy chain C
6bcy chain D
6bcy chain G
6bcy chain H
6bd1 chain C
6bd1 chain D
6bd1 chain G
6bd1 chain H
6bd2 chain C
6bqt chain C
6bqt chain F
6bqt chain I
6bqt chain L
6zeg chain A
6zeg chain B
6zei chain A
6zei chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S213 KNSAAYHS KGKELLA 1 9 - - - - - - 9 - - - - - - - - - - - - - T253 QVASNGAT LPSALSA 6 143 30 - 16 16 - - - - 5 4 5 4 30 28 - - 3 2 - - S259 ATLPSALS ASKSNLV 10 252 6 - 9 6 15 12 27 - 16 10 30 30 28 24 6 2 8 1 17 5 S261 LPSALSAS KSNLVIS 10 1141 53 - 33 30 74 69 99 - 97 57 89 81 88 80 23 6 105 44 95 18 S263 SALSASKS NLVISDP 10 900 79 - 69 59 11 7 90 - 52 29 98 90 88 80 5 1 25 8 91 18 S291 APFVGRMS AQESTPI 3 103 - - - - - - - - 12 8 29 28 14 12 - - - - - - T296 RMSAQEST PIMNGVT 5 136 - - - - - - 9 - 7 3 18 18 13 12 - - - - 47 9 T303 TPIMNGVT GPDGEDY 5 241 39 - 63 42 - - - - 12 5 20 20 21 19 - - - - - - S311 GPDGEDYS PWADRKA 4 39 - - - - - - - - - - - - 4 4 6 1 8 3 4 9 S323 RKAAQPKS LSPPQSQ 3 33 - - - - - - 9 - 11 5 - - 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S213 KNSAAYHS KGKELLA - - - - - - - - - - - T253 QVASNGAT LPSALSA -0.091 - - - - - - -0.091 - - - S259 ATLPSALS ASKSNLV -1.2e-6 - - - - - -9.6e-3 -2.0e-5 - - - S261 LPSALSAS KSNLVIS -7.9e-7 - -1.7e-7 -0.079 - -5.3e-9 0.59 -1.2e-4 - 1.4e-3 -0.9 S263 SALSASKS NLVISDP -0.018 - -2.3e-13 - - -0.21 9.6e-6 0.78 - - -0.16 S291 APFVGRMS AQESTPI -5.6e-8 - - - - - -5.6e-8 - - - - T296 RMSAQEST PIMNGVT - - - - - - - - - - - T303 TPIMNGVT GPDGEDY -0.002 - 0.97 - - - -4.9e-6 -0.41 - - - S311 GPDGEDYS PWADRKA - - - - - - - - - - - S323 RKAAQPKS LSPPQSQ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S213
T253
S259
S261
S263
S291
T296
T303
S311
S323
S325
S329
S334
S336
Y337
S338
T340
S346
T348
S352
Y353
T360
S365
S366
S384
S391
T392
S395
S440
S446
S452
S453
S454
T455
S484
S492
S499
Y505
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation CCRCC S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation COAD S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation GBM S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation HNSCC S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation LSCC S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation LUAD S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation OV S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation PDAC S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation UCEC S213 T253 S259 S261 S263 S291 T296 T303 S311 S323 S325 S329 S334 S336 Y337 S338 T340 S346 T348 S352 Y353 T360 S365 S366 S384 S391 T392 S395 S440 S446 S452 S453 S454 T455 S484 S492 S499 Y505 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S213
T253
S259
S261
S263
S291
T296
T303
S311
S323
S325
S329
S334
S336
Y337
S338
T340
S346
T348
S352
Y353
T360
S365
S366
S384
S391
T392
S395
S440
S446
S452
S453
S454
T455
S484
S492
S499
Y505
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S213
T253
S259
S261
S263
S291
T296
T303
S311
S323
S325
S329
S334
S336
Y337
S338
T340
S346
T348
S352
Y353
T360
S365
S366
S384
S391
T392
S395
S440
S446
S452
S453
S454
T455
S484
S492
S499
Y505
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.