FYB1: FYN binding protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ri9 chain A
2gtj chain A
2gto chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S28 FRVTGPNS SSGIQAR 3 64 - - 8 8 - - - - 13 6 15 14 - - - - - - - - S29 RVTGPNSS SGIQARK 1 9 - - - - - - - - - - - - 5 4 - - - - - - S30 VTGPNSSS GIQARKN 4 32 - - - - - - - - - - 5 5 4 4 - - 5 1 5 3 S46 FNNQGNAS PPAGPSN 7 1015 - - 95 80 - - 90 - 75 42 98 90 110 101 - - 92 39 85 18 S52 ASPPAGPS NVPKFGS 1 26 - - - - - - - - 16 10 - - - - - - - - - - S97 QRFGTPAS LTTRDPE 1 9 - - - - - - - - - - - - - - - - - - 7 2 S184 KGKFMSAS QDLEPKP 7 859 - - 91 69 - - 35 - 98 55 79 71 97 89 - - 91 39 41 4 S205 FGQKPPLS TENSHED 3 39 - - 9 6 - - 18 - - - - - - - - - 5 1 - - T206 GQKPPLST ENSHEDE 4 47 - - 9 6 - - 9 - - - - - 8 9 - - 5 1 - - S209 PPLSTENS HEDESPM 7 1031 - - 99 76 - - 99 - 103 60 98 89 110 101 - - 105 44 38 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S28 FRVTGPNS SSGIQAR - - - - - - - - - - - S29 RVTGPNSS SGIQARK - - - - - - - - - - - S30 VTGPNSSS GIQARKN - - - - - - - - - - - S46 FNNQGNAS PPAGPSN 2.5e-20 - 5.7e-13 - - 3.3e-6 0.75 3.8e-3 - 5.7e-5 4.0e-4 S52 ASPPAGPS NVPKFGS - - - - - - - - - - - S97 QRFGTPAS LTTRDPE - - - - - - - - - - - S184 KGKFMSAS QDLEPKP 2.0e-5 - 2.8e-19 - - 0.01 -0.056 -0.9 - 1 - S205 FGQKPPLS TENSHED - - - - - - - - - - - T206 GQKPPLST ENSHEDE - - - - - - - - - - - S209 PPLSTENS HEDESPM 1.2e-26 - 3.5e-25 - - 1.2e-7 -0.51 3.1e-3 - 3.2e-9 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S28
S29
S30
S46
S52
S97
S184
S205
T206
S209
S214
S225
S235
S245
S256
S276
S329
S432
T443
S445
S457
T461
S558
Y571
S573
S734
Y771
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation CCRCC S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation COAD S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation GBM S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation HNSCC S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation LSCC S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation LUAD S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation OV S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation PDAC S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation UCEC S28 S29 S30 S46 S52 S97 S184 S205 T206 S209 S214 S225 S235 S245 S256 S276 S329 S432 T443 S445 S457 T461 S558 Y571 S573 S734 Y771 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S28
S29
S30
S46
S52
S97
S184
S205
T206
S209
S214
S225
S235
S245
S256
S276
S329
S432
T443
S445
S457
T461
S558
Y571
S573
S734
Y771
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S28
S29
S30
S46
S52
S97
S184
S205
T206
S209
S214
S225
S235
S245
S256
S276
S329
S432
T443
S445
S457
T461
S558
Y571
S573
S734
Y771
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.