HNRNPK: heterogeneous nuclear ribonucleoprotein K
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1j5k chain A
1khm chain A
1zzi chain A
1zzi chain B
1zzj chain A
1zzj chain B
1zzj chain C
1zzk chain A
7cre chain A
7cru chain B
7cru chain D
7rjk chain C
7rjk chain D
7rjo chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S36 EEQAFKRS RNTDEMV 4 92 - - 8 6 - - - - - - 5 5 - - 50 10 - - 6 2 T39 AFKRSRNT DEMVELR 5 76 - - - - 5 4 - - - - 10 10 5 4 21 4 - - 11 2 T70 KNIKALRT DYNASVS 1 17 - - - - - - - - - - - - - - - - - - 12 5 S75 LRTDYNAS VSVPDSS 4 73 - - - - 4 5 37 - - - 10 9 4 4 - - - - - - S77 TDYNASVS VPDSSGP 7 268 - - - - - - 53 - 55 34 30 27 12 11 7 1 3 2 24 9 S89 SGPERILS ISADIET 3 56 - - 7 7 - - 35 - 5 2 - - - - - - - - - - S116 EEGLQLPS PTATSQL 9 816 - - 44 39 96 100 62 - 78 48 34 29 26 24 39 12 86 34 49 16 T118 GLQLPSPT ATSQLPL 7 367 - - 49 31 43 46 10 - 31 20 - - - - 21 4 56 20 29 7 T120 QLPSPTAT SQLPLES 6 105 - - 24 23 4 5 - - 5 2 4 4 12 13 - - 6 3 - - S121 LPSPTATS QLPLESD 6 66 - - 8 6 - - - - 11 7 - - 9 8 6 2 3 2 4 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S36 EEQAFKRS RNTDEMV 0.94 - - - - - - - 0.94 - - T39 AFKRSRNT DEMVELR - - - - - - - - - - - T70 KNIKALRT DYNASVS - - - - - - - - - - - S75 LRTDYNAS VSVPDSS - - - - - - - - - - - S77 TDYNASVS VPDSSGP 0.97 - - - - -0.22 0.19 - - - - S89 SGPERILS ISADIET - - - - - - - - - - - S116 EEGLQLPS PTATSQL -0.15 - -3.2e-3 1.9e-4 - -2.9e-8 0.52 3.1e-3 0.018 0.045 0.38 T118 GLQLPSPT ATSQLPL -0.039 - -9.9e-4 -0.46 - -1.2e-3 - - - 1.7e-3 - T120 QLPSPTAT SQLPLES -5.9e-3 - -5.9e-3 - - - - - - - - S121 LPSPTATS QLPLESD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S36
T39
T70
S75
S77
S89
S116
T118
T120
S121
S127
S154
T176
S216
Y280
S284
S379
Y380
T393
S401
S417
S420
S430
T440
S454
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation CCRCC S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation COAD S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation GBM S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation HNSCC S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation LSCC S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation LUAD S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation OV S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation PDAC S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation UCEC S36 T39 T70 S75 S77 S89 S116 T118 T120 S121 S127 S154 T176 S216 Y280 S284 S379 Y380 T393 S401 S417 S420 S430 T440 S454 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S36
T39
T70
S75
S77
S89
S116
T118
T120
S121
S127
S154
T176
S216
Y280
S284
S379
Y380
T393
S401
S417
S420
S430
T440
S454
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S36
T39
T70
S75
S77
S89
S116
T118
T120
S121
S127
S154
T176
S216
Y280
S284
S379
Y380
T393
S401
S417
S420
S430
T440
S454
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.