Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2fc8 chain A
2fc9 chain A
2krr chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S28 PKEVEEDS EDEEMSE 10 708 98 - 4 4 28 32 63 - 50 29 73 56 57 54 12 5 42 18 67 16 S34 DSEDEEMS EDEEDDS 10 633 44 - 8 7 13 13 37 - 97 55 59 48 29 22 5 1 84 37 65 9 S41 SEDEEDDS SGEEVVI 10 783 7 - 32 29 28 25 90 - 104 58 10 10 110 91 14 5 95 41 31 3 S42 EDEEDDSS GEEVVIP 10 464 113 - 7 7 81 89 8 - 13 6 10 9 4 4 7 1 51 22 28 4 S67 SAKKVVVS PTKKVAV 10 1553 122 - 103 80 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18 T76 TKKVAVAT PAKKAAV 10 1348 122 - 12 12 86 93 99 - 102 59 108 99 105 93 83 19 100 43 95 18 T84 PAKKAAVT PGKKAAA 10 1065 102 - 11 10 15 12 90 - 67 37 108 96 102 89 76 17 90 38 89 16 T92 PGKKAAAT PAKKTVT 3 61 - - - - - - 9 - - - - - - - 20 6 - - 26 - T99 TPAKKTVT PAKAVTT 5 255 23 - - - - - - - - - 35 31 35 32 54 13 23 9 - - T105 VTPAKAVT TPGKKGA 1 9 - - - - - - - - - - - - - - 7 2 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S28 PKEVEEDS EDEEMSE 6e-24 - - 8.2e-3 - 7.5e-4 1.1e-14 3.4e-7 - 0.083 3.3e-5 S34 DSEDEEMS EDEEDDS 1.8e-20 - - - - 1.1e-5 1.1e-11 6.0e-4 - 8.5e-5 - S41 SEDEEDDS SGEEVVI 3.4e-14 - -0.063 4.5e-3 - 3.2e-6 - 3.6e-16 - 1.6e-3 - S42 EDEEDDSS GEEVVIP 4.6e-8 - - 8.5e-17 - - - - - -0.55 - S67 SAKKVVVS PTKKVAV 2.7e-122 - 1.5e-18 1.5e-29 - 2.4e-17 3.4e-35 9.8e-28 2.1e-9 1.4e-10 0.023 T76 TKKVAVAT PAKKAAV 4.2e-74 - - 7.1e-11 - 9.3e-11 5.6e-34 2.1e-21 1.8e-6 4.3e-7 2.2e-4 T84 PAKKAAVT PGKKAAA 4e-39 - - - - 0.44 1.4e-32 3.1e-26 0.014 2e-8 0.47 T92 PGKKAAAT PAKKTVT - - - - - - - - - - - T99 TPAKKTVT PAKAVTT 2e-26 - - - - - 3e-17 3.8e-10 2.0e-4 - - T105 VTPAKAVT TPGKKGA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S28
S34
S41
S42
S67
T76
T84
T92
T99
T105
T106
T121
S145
S153
S184
S206
T213
T214
S328
S356
T367
T405
S458
S460
S479
T480
S482
S494
S496
T498
T501
S532
S542
S563
S580
T583
T587
S591
S595
T606
S608
S619
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation CCRCC S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation COAD S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation GBM S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation HNSCC S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation LSCC S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation LUAD S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation OV S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation PDAC S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation UCEC S28 S34 S41 S42 S67 T76 T84 T92 T99 T105 T106 T121 S145 S153 S184 S206 T213 T214 S328 S356 T367 T405 S458 S460 S479 T480 S482 S494 S496 T498 T501 S532 S542 S563 S580 T583 T587 S591 S595 T606 S608 S619 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S28
S34
S41
S42
S67
T76
T84
T92
T99
T105
T106
T121
S145
S153
S184
S206
T213
T214
S328
S356
T367
T405
S458
S460
S479
T480
S482
S494
S496
T498
T501
S532
S542
S563
S580
T583
T587
S591
S595
T606
S608
S619
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S28
S34
S41
S42
S67
T76
T84
T92
T99
T105
T106
T121
S145
S153
S184
S206
T213
T214
S328
S356
T367
T405
S458
S460
S479
T480
S482
S494
S496
T498
T501
S532
S542
S563
S580
T583
T587
S591
S595
T606
S608
S619
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.