CDK5R1: cyclin dependent kinase 5 regulatory subunit 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1h4l chain D
1h4l chain E
1ung chain D
1ung chain E
1unh chain D
1unh chain E
1unl chain D
1unl chain E
3o0g chain D
3o0g chain E
6ldp chain A
6ldp chain B
7cng chain A
7cng chain B
7vdp chain C
7vdp chain D
7vdq chain C
7vdq chain D
7vdr chain C
7vdr chain D
7vds chain C
7vds chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S45 DKNLKRHS IISVLPW 1 9 - - - - - - 9 - - - - - - - - - - - - - S73 KKVQPNSS YQNNITH 1 18 - - - - - - 18 - - - - - - - - - - - - - T138 PAVTSAGT PKRVIVQ 1 35 - - - - - - 35 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S45 DKNLKRHS IISVLPW - - - - - - - - - - - S73 KKVQPNSS YQNNITH - - - - - - - - - - - T138 PAVTSAGT PKRVIVQ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S45
S73
T138
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S45 S73 T138 protein RNA SCNV methylation CCRCC S45 S73 T138 protein RNA SCNV methylation COAD S45 S73 T138 protein RNA SCNV methylation GBM S45 S73 T138 protein RNA SCNV methylation HNSCC S45 S73 T138 protein RNA SCNV methylation LSCC S45 S73 T138 protein RNA SCNV methylation LUAD S45 S73 T138 protein RNA SCNV methylation OV S45 S73 T138 protein RNA SCNV methylation PDAC S45 S73 T138 protein RNA SCNV methylation UCEC S45 S73 T138 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S45
S73
T138
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S45
S73
T138
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.