ZEB1: zinc finger E-box binding homeobox 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T25 NNVTNYNT VVETNSD 2 17 - - - - - - 9 - - - - - - - - - - - 5 3 T29 NYNTVVET NSDSDDE 8 283 18 - 42 36 - - 35 - 26 17 5 4 47 44 - - 2 1 6 - S31 NTVVETNS DSDDEDK 8 200 13 - 16 15 - - 18 - 35 21 20 18 4 3 - - 5 3 27 2 S33 VVETNSDS DDEDKLH 7 436 - - 34 24 - - 63 - 33 21 40 35 23 20 - - 65 30 41 7 S46 LHIVEEES VTDAADC 1 6 - - - - - - - - - - - - - - - - - - 6 - T48 IVEEESVT DAADCEG 7 178 - - 13 4 - - 26 - 52 26 10 10 9 8 - - 5 2 11 2 S114 VKDDECES DAENEQN 8 411 9 - 29 28 - - 43 - 62 37 24 20 24 20 - - 37 19 45 14 T151 EEDQRQGT PEASGHD 3 117 - - - - - - 54 - - - - - 5 4 - - - - 38 16 S155 RQGTPEAS GHDENGT 2 19 - - - - 5 4 - - - - 5 5 - - - - - - - - S313 LKTSQCSS PSLSASP 9 971 61 - 30 28 23 22 99 - 58 34 98 91 97 88 - - 91 38 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T25 NNVTNYNT VVETNSD - - - - - - - - - - - T29 NYNTVVET NSDSDDE -9.3e-3 - 2.3e-3 - - -2.2e-4 - -1.1e-4 - - - S31 NTVVETNS DSDDEDK -1.7e-4 - - - - -4.3e-4 -0.072 - - - - S33 VVETNSDS DDEDKLH 0.98 - -0.57 - - -0.18 -0.33 -0.89 - 2.3e-3 - S46 LHIVEEES VTDAADC - - - - - - - - - - - T48 IVEEESVT DAADCEG -1.9e-5 - - - - -1.9e-5 - - - - - S114 VKDDECES DAENEQN -7.1e-6 - 0.14 - - -5.8e-3 -0.036 -0.022 - -0.37 -9.4e-6 T151 EEDQRQGT PEASGHD -0.086 - - - - - - - - - -0.087 S155 RQGTPEAS GHDENGT - - - - - - - - - - - S313 LKTSQCSS PSLSASP 0.035 - 0.74 -9.7e-3 - 0.073 0.13 0.004 - 1.1e-12 -5.3e-8
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T25
T29
S31
S33
S46
T48
S114
T151
S155
S313
S315
S317
S319
S322
S342
S447
S455
Y477
S478
S483
S575
T577
S583
S641
S642
S645
S646
S679
S686
T695
S698
S700
S701
T702
S704
S846
S879
S887
T890
S995
T996
S1016
S1018
S1022
S1027
T1029
S1036
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation CCRCC T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation COAD T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation GBM T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation HNSCC T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation LSCC T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation LUAD T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation OV T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation PDAC T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation UCEC T25 T29 S31 S33 S46 T48 S114 T151 S155 S313 S315 S317 S319 S322 S342 S447 S455 Y477 S478 S483 S575 T577 S583 S641 S642 S645 S646 S679 S686 T695 S698 S700 S701 T702 S704 S846 S879 S887 T890 S995 T996 S1016 S1018 S1022 S1027 T1029 S1036 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T25
T29
S31
S33
S46
T48
S114
T151
S155
S313
S315
S317
S319
S322
S342
S447
S455
Y477
S478
S483
S575
T577
S583
S641
S642
S645
S646
S679
S686
T695
S698
S700
S701
T702
S704
S846
S879
S887
T890
S995
T996
S1016
S1018
S1022
S1027
T1029
S1036
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T25
T29
S31
S33
S46
T48
S114
T151
S155
S313
S315
S317
S319
S322
S342
S447
S455
Y477
S478
S483
S575
T577
S583
S641
S642
S645
S646
S679
S686
T695
S698
S700
S701
T702
S704
S846
S879
S887
T890
S995
T996
S1016
S1018
S1022
S1027
T1029
S1036
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.