Protein: ENSP00000319684
Gene: TNS2

LinkedOmicsKB © 2022-2023 Zhang Lab

TNS2:
tensin 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S33PRKAEPHSFREKVFR981074-8868797445-322060582220--9237329
T56CKVTIDGTGVSCRVC6266--3322----7234323433205--3113
S59TIDGTGVSCRVCKVA393--2724------109------194
T91PVELRRNTAPVRRIE10129765-71649710099-462510395110101631310544879
S102RRIEHLGSTKSLNHS101553122-103809710099-10862108991101018319105449518
T103RIEHLGSTKSLNHSK262----2331------------62
S105EHLGSTKSLNHSKQR19----27--------------
S118QRSTLPRSFSLDPLM93819---38439-27184036547238167118
S120STLPRSFSLDPLMER101544122-103809710090-10862108991101018319105449518
T433PEKIKGSTPRNDPSV117--------------143----
Showing 1 to 10 of 69 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S33PRKAEPHSFREKVFR-5.1e-37--1.7e-25-3.6e-14--6.2e-7-1.9e-7-7.6e-4-0.66-
T56CKVTIDGTGVSCRVC-4e-25--0.091----1.4e-16-1.1e-9---3.1e-6
S59TIDGTGVSCRVCKVA-4.9e-7--4.9e-7--------
T91PVELRRNTAPVRRIE-2.8e-52--5.9e-11-1.6e-13--7.3e-12-1.4e-33-4.1e-31-0.115.9e-9-
S102RRIEHLGSTKSLNHS-3.6e-145--7.2e-28-2e-28--7.5e-21-3.8e-35-4.3e-33-1.5e-8-1.5e-8-3.6e-8
T103RIEHLGSTKSLNHSK-2.7e-9---2.7e-9-------
S105EHLGSTKSLNHSKQR-----------
S118QRSTLPRSFSLDPLM-1e-51---1.6e-19--3.5e-11-9.7e-21---1.0e-5-1.0e-5
S120STLPRSFSLDPLMER-1.4e-149--8.5e-21-1.1e-30--2.3e-23-4.8e-35-2.3e-34-1.7e-9-4.6e-12-9.8e-8
T433PEKIKGSTPRNDPSV-----------
Showing 1 to 10 of 69 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationCCRCCS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationCOADS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationGBMS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationHNSCCS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationLSCCS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationLUADS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationOVS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationPDACS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylationUCECS33T56S59T91S102T103S105S118S120T433S455Y456S466S470S481Y483S498T571S589Y610T615S629Y633S637S646S648Y652Y654Y673S769Y770S811S820S825S830S832S835S845Y846T889S893T910T914S915S916T929S931T933T937S941S972S975T977S981S982S991S996S1000S1003S1095S1096T1118S1167S1169T1182S1247T1254S1306T1356proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.