Protein: ENSP00000320828
Gene: EPS8L2

LinkedOmicsKB © 2022-2023 Zhang Lab

EPS8L2:
EPS8 like 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S28SDGVAKMSPKDLFEQ4246122---------15154036--135--
S100LLQVNDQSLRLLDIE134------------1816------
S108LRLLDIESQEELEDF588----72--73552625----62
T125PTVQRSQTVLNQLRY18--44----------------
T184GKKMRPQTLKGHQEK9103488-70507272--6037103941029220568275915
S197EKIRQRQSILPPPQG996542-82613033--9656108991101017154224815
S217FQHRGGDSPEAKNRV1092997-8772202518-102599385605446121266318
S231VGPQVPLSEPGFRRR339--54----116--------13-
S240PGFRRRESQEEPRAV101466113-9977889178-1086210395105978218105448318
T303APAEGVLTLRARPPS9100457-21209395--74441089910293152105432112
Showing 1 to 10 of 30 rows
102550
rows per page

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S28SDGVAKMSPKDLFEQ-1.3e-8-------1.3e-8---
S100LLQVNDQSLRLLDIE-----------
S108LRLLDIESQEELEDF-0.67-------0.67---
T125PTVQRSQTVLNQLRY-----------
T184GKKMRPQTLKGHQEK-3.2e-15--0.0050.39--4.3e-8-3.5e-30-4e-12-1.1e-30.098
S197EKIRQRQSILPPPQG-2.7e-21--1.3e-3-9.0e-4--5.5e-6-9.2e-22-3.6e-10-0.013-0.53
S217FQHRGGDSPEAKNRV-1.1e-4--1.1e-5-0.41--5.9e-8-0.130.029-0.89--0.92
S231VGPQVPLSEPGFRRR-----------
S240PGFRRRESQEEPRAV-6.2e-23-8.4e-4-0.045--2.8e-15-1.4e-28-1.1e-150.012-4.7e-4-0.22
T303APAEGVLTLRARPPS-1.6e-15--0.030.84--7.9e-16-3.7e-31-1.2e-22-1.1e-121.3e-3
Showing 1 to 10 of 30 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationCCRCCS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationCOADS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationGBMS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationHNSCCS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationLSCCS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationLUADS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationOVS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationPDACS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylationUCECS28S100S108T125T184S197S217S231S240T303S310S368S442S449S452S455S459S463T465S466T469S479S480S535S570T572S578S693S695S706proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.