TACC1: transforming acidic coiled-coil containing protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S44 GDPEEEDS QAETKSL 7 1047 - - 99 76 - - 99 - 108 62 108 98 106 97 - - 89 37 50 18 T48 EEDSQAET KSLSFSS 4 252 - - - - - - 45 - 50 31 64 56 - - - - - - 6 - S50 DSQAETKS LSFSSDS 3 78 - - - - - - - - - - 20 18 8 8 - - - - 18 6 S52 QAETKSLS FSSDSEG 2 53 - - - - - - 45 - - - - - 4 4 - - - - - - S54 ETKSLSFS SDSEGNF 1 8 - - - - - - - - - - - - 4 4 - - - - - - S55 TKSLSFSS DSEGNFE 5 67 - - - - - - 6 - - - 10 10 14 12 7 2 - - 6 - S57 SLSFSSDS EGNFETP 9 537 73 - 17 16 - - 52 - 40 23 79 73 36 33 6 1 3 2 67 16 T63 DSEGNFET PEAETPI 5 154 9 - - - - - - - 5 2 49 46 18 16 - - - - - 9 T68 FETPEAET PIRSPFK 2 29 - - - - - - 19 - - - 5 5 - - - - - - - - S72 EAETPIRS PFKESCD 1 26 - - - - - - 26 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S44 GDPEEEDS QAETKSL 1.5e-14 - 1.9e-8 - - -0.055 6.2e-24 1.2e-6 - 2.6e-3 -4.7e-3 T48 EEDSQAET KSLSFSS 1.7e-4 - - - - -0.13 8.8e-12 - - - - S50 DSQAETKS LSFSSDS -3.0e-4 - - - - - -3.0e-4 - - - - S52 QAETKSLS FSSDSEG - - - - - - - - - - - S54 ETKSLSFS SDSEGNF - - - - - - - - - - - S55 TKSLSFSS DSEGNFE - - - - - - - - - - - S57 SLSFSSDS EGNFETP 0.12 - - - - 0.066 5.8e-10 -0.14 - - -6.5e-4 T63 DSEGNFET PEAETPI 0.65 - - - - - 0.65 - - - - T68 FETPEAET PIRSPFK - - - - - - - - - - - S72 EAETPIRS PFKESCD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S44
T48
S50
S52
S54
S55
S57
T63
T68
S72
S91
S94
S129
S131
S147
S153
S179
S208
S218
S225
S248
T250
T257
S267
T275
S276
S287
S300
T302
S305
S315
S316
S347
T348
T350
S465
T504
S513
S518
S550
T569
S577
S586
S591
S599
S666
S687
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation CCRCC S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation COAD S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation GBM S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation HNSCC S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation LSCC S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation LUAD S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation OV S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation PDAC S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation UCEC S44 T48 S50 S52 S54 S55 S57 T63 T68 S72 S91 S94 S129 S131 S147 S153 S179 S208 S218 S225 S248 T250 T257 S267 T275 S276 S287 S300 T302 S305 S315 S316 S347 T348 T350 S465 T504 S513 S518 S550 T569 S577 S586 S591 S599 S666 S687 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S44
T48
S50
S52
S54
S55
S57
T63
T68
S72
S91
S94
S129
S131
S147
S153
S179
S208
S218
S225
S248
T250
T257
S267
T275
S276
S287
S300
T302
S305
S315
S316
S347
T348
T350
S465
T504
S513
S518
S550
T569
S577
S586
S591
S599
S666
S687
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S44
T48
S50
S52
S54
S55
S57
T63
T68
S72
S91
S94
S129
S131
S147
S153
S179
S208
S218
S225
S248
T250
T257
S267
T275
S276
S287
S300
T302
S305
S315
S316
S347
T348
T350
S465
T504
S513
S518
S550
T569
S577
S586
S591
S599
S666
S687
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.