FARP1: FERM, ARH/RhoGEF and pleckstrin domain protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4h6y chain A
4h6y chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S12 EQRPTPGS RLGAPEN 2 18 - - - - - - 9 - - - - - - - 7 2 - - - - S20 RLGAPENS GISTLER 8 386 49 - 55 35 - - 81 - - - 28 26 4 3 14 3 19 10 46 13 S23 APENSGIS TLERGQK 10 325 44 - 45 36 13 14 36 - 34 21 10 9 4 5 7 2 23 10 12 - T24 PENSGIST LERGQKP 10 1264 79 - 62 40 88 91 80 - 64 35 99 91 97 88 83 19 105 44 84 15 T34 RGQKPPPT PSGKLVS 10 863 105 - 103 80 31 23 72 - 18 10 64 57 81 76 28 6 58 24 25 2 S332 KPKPVLFS RGSSFRF 1 33 - - 17 16 - - - - - - - - - - - - - - - - S336 VLFSRGSS FRFSGRT 5 185 26 - - - - - 35 - - - - - - - 36 7 15 7 50 9 S340 RGSSFRFS GRTQKQV 10 947 89 - 63 49 22 31 63 - 81 43 78 70 52 50 50 11 59 23 95 18 S370 RKHSKIHS IRSLASQ 5 61 8 - 4 4 - - 17 - - - 10 9 5 4 - - - - - - S373 SKIHSIRS LASQPTE 5 110 13 - 4 4 - - 9 - - - 39 32 5 4 - - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S12 EQRPTPGS RLGAPEN - - - - - - - - - - - S20 RLGAPENS GISTLER -2.3e-10 - -3.8e-5 - - - -8.7e-5 - - - -3.4e-3 S23 APENSGIS TLERGQK 0.47 - 0.055 - - 0.095 - - - -0.02 - T24 PENSGIST LERGQKP -1.2e-20 - 0.47 -8.6e-10 - 1.4e-4 -4.3e-25 -5.5e-15 0.38 -2.3e-3 -9.2e-6 T34 RGQKPPPT PSGKLVS 1.2e-8 - 9.6e-17 5.2e-5 - - -8.3e-3 1.7e-5 - -0.21 - S332 KPKPVLFS RGSSFRF - - - - - - - - - - - S336 VLFSRGSS FRFSGRT - - - - - - - - - - - S340 RGSSFRFS GRTQKQV 7.3e-5 - 0.37 0.98 - 6.2e-8 -0.14 -0.94 0.035 0.019 0.048 S370 RKHSKIHS IRSLASQ - - - - - - - - - - - S373 SKIHSIRS LASQPTE -7.2e-3 - - - - - -7.2e-3 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S12
S20
S23
T24
T34
S332
S336
S340
S370
S373
S376
T379
S383
S389
S392
T396
S403
S408
S418
S424
S427
S433
S445
T448
T475
S477
S481
S484
S487
T497
S503
S510
S514
T525
S582
S613
S833
S861
S863
S871
S872
S878
T883
S889
S894
S896
T898
S899
S1004
S1038
S1042
Y1045
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation CCRCC S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation COAD S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation GBM S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation HNSCC S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation LSCC S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation LUAD S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation OV S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation PDAC S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation UCEC S12 S20 S23 T24 T34 S332 S336 S340 S370 S373 S376 T379 S383 S389 S392 T396 S403 S408 S418 S424 S427 S433 S445 T448 T475 S477 S481 S484 S487 T497 S503 S510 S514 T525 S582 S613 S833 S861 S863 S871 S872 S878 T883 S889 S894 S896 T898 S899 S1004 S1038 S1042 Y1045 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S12
S20
S23
T24
T34
S332
S336
S340
S370
S373
S376
T379
S383
S389
S392
T396
S403
S408
S418
S424
S427
S433
S445
T448
T475
S477
S481
S484
S487
T497
S503
S510
S514
T525
S582
S613
S833
S861
S863
S871
S872
S878
T883
S889
S894
S896
T898
S899
S1004
S1038
S1042
Y1045
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S12
S20
S23
T24
T34
S332
S336
S340
S370
S373
S376
T379
S383
S389
S392
T396
S403
S408
S418
S424
S427
S433
S445
T448
T475
S477
S481
S484
S487
T497
S503
S510
S514
T525
S582
S613
S833
S861
S863
S871
S872
S878
T883
S889
S894
S896
T898
S899
S1004
S1038
S1042
Y1045
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.