Protein: ENSP00000323720
Gene: MED14

LinkedOmicsKB © 2022-2023 Zhang Lab

MED14:
mediator complex subunit 14

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S617TNAKRKLSDDPCPVE101422122-10380838754-10159108991101014712105448918
S977NQDARRRSVNEDDNP931415-412130329-513010944--32467
S986NEDDNPPSPIGGDMM101176103-5544928790-10862695993869386357718
S995IGGDMMDSLISQLQP4318-------7255------4-
S998DMMDSLISQLQPPPQ717834-24134518-2618541413------
S1112RAGNWPGSPQVSGPS1088268-6949141345-96555448948452931107813
S1116WPGSPQVSGPSPAAR35630-88------55--------
S1119SPQVSGPSPAARMPG92786-16167219-6339372219214--529
S1128AARMPGMSPANPSLH4848-44--36-----------1913
S1133GMSPANPSLHSPVPD34318-44--------------134
Showing 1 to 10 of 12 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S617TNAKRKLSDDPCPVE4.5e-26--7.6e-94.3e-16-2.4e-149e-151.5e-120.0220.0160.71
S977NQDARRRSVNEDDNP-0.65--0.210.004--0.015-----
S986NEDDNPPSPIGGDMM7.2e-5--2.4e-31.1e-7--0.0252.3e-121.9e-6--3.1e-40.022
S995IGGDMMDSLISQLQP-----------
S998DMMDSLISQLQPPPQ-0.017--0.12---0.071-----
S1112RAGNWPGSPQVSGPS-0.79-0.036---0.230.76-1.3e-4-0.170.057
S1116WPGSPQVSGPSPAAR-----------
S1119SPQVSGPSPAARMPG0.014-----1.3e-7-0.069---
S1128AARMPGMSPANPSLH-----------
S1133GMSPANPSLHSPVPD-----------
Showing 1 to 10 of 12 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationCCRCCS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationCOADS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationGBMS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationHNSCCS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationLSCCS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationLUADS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationOVS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationPDACS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylationUCECS617S977S986S995S998S1112S1116S1119S1128S1133S1136S1144proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.