HSPA5: heat shock protein family A (Hsp70) member 5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3iuc chain A
3iuc chain C
3ldl chain A
3ldl chain B
3ldn chain A
3ldn chain B
3ldo chain A
3ldo chain B
3ldp chain A
3ldp chain B
5e84 chain A
5e84 chain B
5e84 chain C
5e84 chain D
5e84 chain E
5e84 chain F
5e85 chain A
5e86 chain A
5evz chain A
5evz chain B
5ex5 chain A
5ex5 chain B
5exw chain A
5exw chain B
5ey4 chain A
5ey4 chain B
5f0x chain A
5f0x chain B
5f1x chain A
5f1x chain B
5f2r chain A
5f2r chain B
5yp8 chain A
5yp8 chain B
5ypa chain A
5ypa chain B
5ypb chain A
5ypb chain B
5ypc chain A
5ypc chain B
5ypc chain C
5ypc chain D
5ype chain A
5ype chain B
5ypf chain A
5ypf chain B
5ypf chain C
5ypf chain D
5ypg chain A
5ypg chain B
5yph chain A
5yph chain B
6asy chain A
6asy chain B
6cz1 chain A
6cz1 chain B
6dfm chain A
6dfm chain B
6dfo chain A
6dfo chain B
6do2 chain A
6do2 chain B
6dws chain A
6dws chain B
6zmd chain A
7n1r chain A
7n1r chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S64 QGNRITPS YVAFTPE 2 14 - - - - - - - - - - - - 4 4 - - - - 6 - T85 DAAKNQLT SNPENTV 5 118 - - - - - - 45 - 11 7 - - - - 7 1 12 5 19 11 S86 AAKNQLTS NPENTVF 6 140 9 - - - - - 35 - 24 15 10 9 - - - - 17 8 11 2 T91 LTSNPENT VFDAKRL 1 9 - - - - - - 9 - - - - - - - - - - - - - T139 IGGGQTKT FAPEEIS 4 80 - - - - - - 9 - 6 4 24 20 9 8 - - - - - - S301 KAKRALSS QHQARIE 2 113 - - - - - - - - 27 19 - - - - 53 14 - - - - S354 EDSDLKKS DIDEIVL 4 84 13 - - - - - - - - - 29 27 4 4 - - 5 2 - - S448 TVVPTKKS QIFSTAS 6 245 22 - - - - - 18 - - - 13 12 27 24 - - 47 20 50 12 S452 TKKSQIFS TASDNQP 1 9 - - - - - - 9 - - - - - - - - - - - - - S455 SQIFSTAS DNQPTVT 3 82 - - 5 4 - - - - 16 10 - - - - - - 31 16 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S64 QGNRITPS YVAFTPE - - - - - - - - - - - T85 DAAKNQLT SNPENTV - - - - - - - - - - - S86 AAKNQLTS NPENTVF -0.11 - - - - -0.11 - - - - - T91 LTSNPENT VFDAKRL - - - - - - - - - - - T139 IGGGQTKT FAPEEIS 4.8e-7 - - - - - 4.8e-7 - - - - S301 KAKRALSS QHQARIE -0.012 - - - - -9.3e-3 - - -0.34 - - S354 EDSDLKKS DIDEIVL 1.3e-5 - - - - - 1.3e-5 - - - - S448 TVVPTKKS QIFSTAS -0.2 - - - - - - 0.021 - -4e-13 6.2e-3 S452 TKKSQIFS TASDNQP - - - - - - - - - - - S455 SQIFSTAS DNQPTVT -1.2e-9 - - - - - - - - -1.2e-9 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S64
T85
S86
T91
T139
S301
S354
S448
S452
S455
T518
T525
T534
S571
S607
S632
S637
T643
T648
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation CCRCC S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation COAD S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation GBM S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation HNSCC S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation LSCC S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation LUAD S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation OV S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation PDAC S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation UCEC S64 T85 S86 T91 T139 S301 S354 S448 S452 S455 T518 T525 T534 S571 S607 S632 S637 T643 T648 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S64
T85
S86
T91
T139
S301
S354
S448
S452
S455
T518
T525
T534
S571
S607
S632
S637
T643
T648
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S64
T85
S86
T91
T139
S301
S354
S448
S452
S455
T518
T525
T534
S571
S607
S632
S637
T643
T648
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.