ULK1: unc-51 like autophagy activating kinase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4wno chain A
4wnp chain A
4wnp chain B
4wnp chain C
4wnp chain D
5ci7 chain A
6hyo chain A
6mnh chain A
6qas chain A
6qas chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S281 HHPFLDAS PSVRKSP 1 17 - - 13 4 - - - - - - - - - - - - - - - - S330 QLQKTLAS PADTAGF 2 61 - - - - - - 9 - - - - - - - 43 9 - - - - S340 DTAGFLHS SRDSGGS 3 64 - - 8 8 - - - - - - - - - - 34 8 - - 6 - S341 TAGFLHSS RDSGGSK 3 41 - - 8 8 - - - - - - - - - - 7 1 - - 13 4 S344 FLHSSRDS GGSKDSS 3 77 - - - - - - 53 - - - - - 4 3 - - - - 13 4 S347 SSRDSGGS KDSSCDT 1 18 - - - - - - 18 - - - - - - - - - - - - - S403 ESHGRTPS PSPPCSS 7 180 49 - 4 4 - - 19 - - - 15 14 9 8 8 1 - - 40 9 S405 HGRTPSPS PPCSSSP 2 31 - - - - - - - - - - - - 9 8 - - - - 14 - S410 SPSPPCSS SPSPSGR 1 7 - - - - - - - - - - - - - - - - - - 7 - S411 PSPPCSSS PSPSGRA 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S281 HHPFLDAS PSVRKSP - - - - - - - - - - - S330 QLQKTLAS PADTAGF - - - - - - - - - - - S340 DTAGFLHS SRDSGGS - - - - - - - - - - - S341 TAGFLHSS RDSGGSK - - - - - - - - - - - S344 FLHSSRDS GGSKDSS - - - - - - - - - - - S347 SSRDSGGS KDSSCDT - - - - - - - - - - - S403 ESHGRTPS PSPPCSS - - - - - - - - - - - S405 HGRTPSPS PPCSSSP - - - - - - - - - - - S410 SPSPPCSS SPSPSGR - - - - - - - - - - - S411 PSPPCSSS PSPSGRA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S281
S330
S340
S341
S344
S347
S403
S405
S410
S411
S424
S450
S459
S465
S467
T468
S469
S477
S479
S495
S522
S533
S538
S539
S544
S556
T575
S583
S588
S605
S623
S630
T636
S638
S639
T654
T660
S694
S716
T717
S719
S750
T755
S758
S761
S763
T764
S775
S781
S1042
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation CCRCC S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation COAD S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation GBM S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation HNSCC S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation LSCC S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation LUAD S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation OV S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation PDAC S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation UCEC S281 S330 S340 S341 S344 S347 S403 S405 S410 S411 S424 S450 S459 S465 S467 T468 S469 S477 S479 S495 S522 S533 S538 S539 S544 S556 T575 S583 S588 S605 S623 S630 T636 S638 S639 T654 T660 S694 S716 T717 S719 S750 T755 S758 S761 S763 T764 S775 S781 S1042 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S281
S330
S340
S341
S344
S347
S403
S405
S410
S411
S424
S450
S459
S465
S467
T468
S469
S477
S479
S495
S522
S533
S538
S539
S544
S556
T575
S583
S588
S605
S623
S630
T636
S638
S639
T654
T660
S694
S716
T717
S719
S750
T755
S758
S761
S763
T764
S775
S781
S1042
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S281
S330
S340
S341
S344
S347
S403
S405
S410
S411
S424
S450
S459
S465
S467
T468
S469
S477
S479
S495
S522
S533
S538
S539
S544
S556
T575
S583
S588
S605
S623
S630
T636
S638
S639
T654
T660
S694
S716
T717
S719
S750
T755
S758
S761
S763
T764
S775
S781
S1042
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.