PGR: progesterone receptor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1a28 chain A
1a28 chain B
1e3k chain A
1e3k chain B
1sqn chain A
1sqn chain B
1sr7 chain A
1sr7 chain B
1zuc chain A
1zuc chain B
2c7a chain A
2c7a chain B
2ovh chain A
2ovm chain A
2w8y chain A
2w8y chain B
3d90 chain A
3d90 chain B
3g8o chain A
3g8o chain B
3hq5 chain A
3hq5 chain B
3kba chain A
3kba chain B
3zr7 chain A
3zr7 chain B
3zra chain A
3zra chain B
3zrb chain A
3zrb chain B
4a2j chain A
4a2j chain B
4apu chain A
4apu chain B
4oar chain A
5cc0 chain A
5cc0 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S20 HVAGGPPS PEVGSPL 8 543 114 - 20 20 - - - - 38 22 5 4 30 28 72 17 42 18 95 18 S25 PPSPEVGS PLLCRPA 3 161 40 - 4 4 - - - - - - - - - - - - - - 95 18 S79 EKTQDQQS LSDVEGA 1 60 - - - - - - - - - - - - - - - - - - 60 - S81 TQDQQSLS DVEGAYS 5 249 97 - 16 15 - - - - 12 5 - - - - - - 15 6 68 15 S99 ATRGAGGS SSSPPEK 1 8 - - - - - - - - - - - - - - - - - - 8 - S100 TRGAGGSS SSPPEKD 1 27 - - - - - - - - - - - - - - - - - - 25 2 S101 RGAGGSSS SPPEKDS 1 21 - - - - - - - - - - - - - - - - - - 10 11 S102 GAGGSSSS PPEKDSG 8 339 78 - 24 23 - - - - 32 15 5 5 5 4 13 2 14 6 95 18 S162 PATQRVLS PLMSRSG 8 664 34 - 17 16 - - - - 17 10 63 59 95 89 83 19 34 15 95 18 S175 SGCKVGDS SGTAAAH 1 12 - - - - - - - - - - - - - - - - - - 12 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S20 HVAGGPPS PEVGSPL -3.1e-5 - 0.8 - - -0.56 - -0.067 -1.8e-3 -2.4e-3 -0.059 S25 PPSPEVGS PLLCRPA -0.37 - - - - - - - - - -0.37 S79 EKTQDQQS LSDVEGA - - - - - - - - - - - S81 TQDQQSLS DVEGAYS -0.17 - - - - - - - - - -0.17 S99 ATRGAGGS SSSPPEK - - - - - - - - - - - S100 TRGAGGSS SSPPEKD - - - - - - - - - - - S101 RGAGGSSS SPPEKDS - - - - - - - - - - - S102 GAGGSSSS PPEKDSG -8.6e-5 - -2.2e-4 - - -0.8 - - - - -4.5e-3 S162 PATQRVLS PLMSRSG -8.8e-28 - - - - - -1.8e-21 -2.5e-28 -0.019 0.057 -6.2e-4 S175 SGCKVGDS SGTAAAH - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S20
S25
S79
S81
S99
S100
S101
S102
S162
S175
S202
S227
S229
S273
S294
S328
Y329
S337
S344
S345
S350
T351
S397
S400
S432
S450
S499
S552
S554
S666
S670
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation CCRCC S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation COAD S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation GBM S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation HNSCC S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation LSCC S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation LUAD S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation OV S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation PDAC S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation UCEC S20 S25 S79 S81 S99 S100 S101 S102 S162 S175 S202 S227 S273 S294 S328 Y329 S337 S344 S345 S350 T351 S397 S400 S432 S450 S499 S552 S554 S666 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S20
S25
S79
S81
S99
S100
S101
S102
S162
S175
S202
S227
S229
S273
S294
S328
Y329
S337
S344
S345
S350
T351
S397
S400
S432
S450
S499
S552
S554
S666
S670
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S20
S25
S79
S81
S99
S100
S101
S102
S162
S175
S202
S227
S229
S273
S294
S328
Y329
S337
S344
S345
S350
T351
S397
S400
S432
S450
S499
S552
S554
S666
S670
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.