Protein: ENSP00000325326
Gene: ZNF335

LinkedOmicsKB © 2022-2023 Zhang Lab

ZNF335:
zinc finger protein 335

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S289KGRLRKWSTSTKSQE595--44171026---------4129-
T344LQRPTPSTPRPRRRP711635-54----641413108--3212-
S976RDGPEPPSPAKTHCV1071887-241513555-713994856356216865713
S991GDSQSSASSPPATSK59041---36--5298--133----
S992DSQSSASSPPATSKA8342--54252881-392454--3571974514
S1007LGLAVPPSPPSAATA101115113-7164151254-108621039510194631423109518
S1127FHIQRLHSPDGRKSG6463------27---4442625676167030364
S1153TQTIILNSDDETLAT2106------27-5029----------
T1157ILNSDDETLATLHTA188-------------------
Showing 1 to 9 of 9 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S289KGRLRKWSTSTKSQE-----------
T344LQRPTPSTPRPRRRP-----------
S976RDGPEPPSPAKTHCV2.5e-20--0.033--1.2e-71.9e-196.4e-12--0.11
S991GDSQSSASSPPATSK-----------
S992DSQSSASSPPATSKA1.7e-9--1.1e-4-1.5e-3----7.1e-4
S1007LGLAVPPSPPSAATA8.3e-8-0.71--8.7e-86.4e-118.7e-3-0.110.13-0.56
S1127FHIQRLHSPDGRKSG5e-8-----2.4e-83.4e-101.1e-4-1.5e-6-
S1153TQTIILNSDDETLAT-1.1e-5-----1.1e-5-----
T1157ILNSDDETLATLHTA-----------
Showing 1 to 9 of 9 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationCCRCCS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationCOADS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationGBMS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationHNSCCS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationLSCCS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationLUADS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationOVS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationPDACS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylationUCECS289T344S976S991S992S1007S1127S1153T1157proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.