SRSF7: serine and arginine rich splicing factor 7
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y122 YAYDCHRY SRRRRSR 3 44 - - 4 4 - - - - 10 6 - - - - - - 13 7 - - S123 AYDCHRYS RRRRSRS 6 227 15 - 8 8 - - 71 - 26 13 4 4 - - - - 56 22 - - S157 SRGRRSRS ASPRRSR 2 43 - - - - - - 28 - - - - - - - - - - - 11 4 S159 GRRSRSAS PRRSRSI 2 92 - - - - - - 45 - - - - - - - - - - - 41 6 S163 RSASPRRS RSISLRR 6 285 - - - - 39 42 72 - 12 6 - - 9 9 - - 4 1 73 18 S165 ASPRRSRS ISLRRSR 6 261 - - - - 33 30 54 - 11 7 - - 9 9 - - 33 13 50 12 S167 PRRSRSIS LRRSRSA 3 59 - - - - 1 7 36 - - - - - - - - - - - 6 9 S171 RSISLRRS RSASLRR 5 263 - - - - 31 40 90 - - - - - 9 8 - - 4 1 62 18 S173 ISLRRSRS ASLRRSR 6 314 - - - - 31 40 90 - 11 7 - - 9 8 - - 31 12 66 9 S175 LRRSRSAS LRRSRSG 4 197 - - - - 19 25 81 - 11 7 - - - - - - - - 45 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y122 YAYDCHRY SRRRRSR - - - - - - - - - - - S123 AYDCHRYS RRRRSRS 1.5e-6 - - - - 1.7e-7 - - - 0.12 - S157 SRGRRSRS ASPRRSR - - - - - - - - - - - S159 GRRSRSAS PRRSRSI - - - - - - - - - - - S163 RSASPRRS RSISLRR 1.4e-7 - - 8.9e-8 - - - - - - 0.036 S165 ASPRRSRS ISLRRSR 1.5e-5 - - 9.2e-7 - - - - - 0.037 0.61 S167 PRRSRSIS LRRSRSA - - - - - - - - - - - S171 RSISLRRS RSASLRR 1.2e-4 - - 2e-7 - - - - - - 0.81 S173 ISLRRSRS ASLRRSR 5.1e-9 - - 1.2e-7 - - - - - 0.003 - S175 LRRSRSAS LRRSRSG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y122
S123
S157
S159
S163
S165
S167
S171
S173
S175
S179
S181
S183
S187
S192
S194
S196
S198
S202
S208
S209
S213
S215
S217
S221
S223
S225
S227
S231
S233
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation CCRCC Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation COAD Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation GBM Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation HNSCC Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation LSCC Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation LUAD Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation OV Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation PDAC Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation UCEC Y122 S123 S157 S159 S163 S165 S167 S171 S173 S175 S179 S181 S183 S187 S192 S194 S196 S198 S202 S208 S209 S213 S215 S217 S221 S223 S225 S227 S231 S233 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y122
S123
S157
S159
S163
S165
S167
S171
S173
S175
S179
S181
S183
S187
S192
S194
S196
S198
S202
S208
S209
S213
S215
S217
S221
S223
S225
S227
S231
S233
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y122
S123
S157
S159
S163
S165
S167
S171
S173
S175
S179
S181
S183
S187
S192
S194
S196
S198
S202
S208
S209
S213
S215
S217
S221
S223
S225
S227
S231
S233
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.