Protein: ENSP00000326550
Gene: TACC3

LinkedOmicsKB © 2022-2023 Zhang Lab

TACC3:
transforming acidic coiled-coil containing protein 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S25ENCDFLFSPPEVTGR619357-------1991010544810--129
S39RSSVLRVSQKENVPP613740---------10109872513411
T59AMKVTFQTPLRDPQT414143-----18---2018--339----
S71PQTHRILSPSMASKL10110496-44344590-9656988810290701691357613
S175MVSPGKVSGSPEQAV16------------------6-
S177SPGKVSGSPEQAVEE1069128-44252080-603434317364781530108318
T196YSLDRRVTPASETLE176--------------6115----
S210EDPCRTESQHKAETP18------------44------
T216ESQHKAETPHGAEEE5133--------63302744357--134
T228EEECKAETPHGAEEE93929---6387-181063571211409514615
Showing 1 to 10 of 23 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S25ENCDFLFSPPEVTGR-0.3--------0.3--
S39RSSVLRVSQKENVPP-0.33----------0.33
T59AMKVTFQTPLRDPQT0.028-----0.028----
S71PQTHRILSPSMASKL1e-67-7.3e-15--3e-95.2e-307.9e-285.8e-37e-130.97
S175MVSPGKVSGSPEQAV-----------
S177SPGKVSGSPEQAVEE3.1e-3--0.63--0.620.043-0.230.620.381.9e-8
T196YSLDRRVTPASETLE-0.73--------0.73--
S210EDPCRTESQHKAETP-----------
T216ESQHKAETPHGAEEE5.2e-9-----5.2e-9----
T228EEECKAETPHGAEEE7.4e-18-----5e-20---2.6e-3
Showing 1 to 10 of 23 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationCCRCCS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationCOADS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationGBMS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationHNSCCS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationLSCCS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationLUADS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationOVS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationPDACS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylationUCECS25S39T59S71S175S177T196S210T216T228T249S250T315S317S402S434T472T481T546S548S558T590Y684proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.