Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2lll chain A
5bnw chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S5 ___MSPPS PGRRREQ 9 300 17 - 4 4 45 36 27 - 24 14 10 9 5 4 54 13 24 10 - - T23 RAAATMAT PLPGRAG 6 424 47 - - - - - - - 19 9 88 81 38 36 - - 2 1 85 18 T34 GRAGGPAT PLSPTRL 10 1290 113 - 73 54 93 95 99 - 50 32 88 82 92 85 83 19 85 34 95 18 S37 GGPATPLS PTRLSRL 10 1142 96 - 96 73 97 100 80 - 81 45 68 61 53 49 61 14 70 30 53 15 S42 PLSPTRLS RLQEKEE 2 20 - - - - - - - - - - - - 4 4 - - 9 3 - - S134 ELDEVNKS AKKREGE 2 17 8 - - - - - - - - - - - - - 8 1 - - - - S154 GRVKDLES LFHRSEV 1 9 - - - - 2 7 - - - - - - - - - - - - - - S168 VELAAALS DKRGLES 6 294 7 - 5 4 - - - - - - 49 44 44 40 - - 8 4 80 9 S175 SDKRGLES DVAELRA 3 25 - - 4 4 2 7 - - - - - - - - 5 3 - - - - S214 DLENRCQS LQEELDF 7 259 30 - 17 16 - - - - 21 11 35 32 33 27 - - 12 4 16 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S5 ___MSPPS PGRRREQ 6.1e-7 - - 2.0e-5 - 0.018 - - 0.24 0.031 - T23 RAAATMAT PLPGRAG -0.58 - - - - - -0.99 -0.059 - - 0.35 T34 GRAGGPAT PLSPTRL -9.1e-13 - -4.1e-5 0.017 - -0.021 -6.3e-15 -5.3e-9 -4.4e-4 4.7e-7 -4.7e-5 S37 GGPATPLS PTRLSRL -1.7e-16 - -7.4e-7 -0.33 - -0.05 -2.3e-17 -7.7e-7 -1.6e-6 9.6e-7 -0.034 S42 PLSPTRLS RLQEKEE - - - - - - - - - - - S134 ELDEVNKS AKKREGE - - - - - - - - - - - S154 GRVKDLES LFHRSEV - - - - - - - - - - - S168 VELAAALS DKRGLES -7.8e-36 - - - - - -1.5e-19 -6.3e-18 - - - S175 SDKRGLES DVAELRA - - - - - - - - - - - S214 DLENRCQS LQEELDF 0.019 - - - - -0.94 1.3e-4 0.76 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S5
T23
T34
S37
S42
S134
S154
S168
S175
S214
S224
S246
S247
Y252
S292
S301
S316
S318
Y319
S322
Y374
S415
S419
S420
S421
S422
S424
S426
T428
S492
S497
T518
S541
S552
S553
S559
S581
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation CCRCC S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation COAD S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation GBM S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation HNSCC S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation LSCC S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation LUAD S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation OV S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation PDAC S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation UCEC S5 T23 T34 S37 S42 S134 S154 S168 S175 S214 S224 S246 S247 Y252 S292 S301 S316 S318 Y319 S322 Y374 S415 S419 S420 S421 S422 S424 S426 T428 S492 S497 T518 S541 S552 S553 S559 S581 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S5
T23
T34
S37
S42
S134
S154
S168
S175
S214
S224
S246
S247
Y252
S292
S301
S316
S318
Y319
S322
Y374
S415
S419
S420
S421
S422
S424
S426
T428
S492
S497
T518
S541
S552
S553
S559
S581
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S5
T23
T34
S37
S42
S134
S154
S168
S175
S214
S224
S246
S247
Y252
S292
S301
S316
S318
Y319
S322
Y374
S415
S419
S420
S421
S422
S424
S426
T428
S492
S497
T518
S541
S552
S553
S559
S581
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.