Protein: ENSP00000327077
Gene: PCM1

LinkedOmicsKB © 2022-2023 Zhang Lab

PCM1:
pericentriolar material 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S56KKKFGVESDKRVTND229--44--------------129
T61VESDKRVTNDISPES652----729---5554--528-
S65KRVTNDISPESSPGV81296--10380838799-1086210899110101--101429518
S68TNDISPESSPGVGRR8377--35276390-412235312624--2296-
S69NDISPESSPGVGRRR8467--441089-37221098882--84384616
T79VGRRRTKTPHTFPHS7393--54--72-11788822927--324815
T82RRTKTPHTFPHSRYM245------28-----------152
S90FPHSRYMSQMSVPEQ594--9872--2412--1412----6-
S93SRYMSQMSVPEQAEL81302--10380838799-1086210899110101--105449518
S110LKQRINFSDLDQRSI8439--1311343710-654363592120--643518
Showing 1 to 10 of 129 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S56KKKFGVESDKRVTND-----------
T61VESDKRVTNDISPES-----------
S65KRVTNDISPESSPGV0.13--2.2e-30.021--0.140.158.6e-6--0.130.066
S68TNDISPESSPGVGRR9.9e-7-0.26--0.441.1e-54.8e-4---
S69NDISPESSPGVGRRR4.2e-5----0.41-9.4e-8--0.0282.4e-5
T79VGRRRTKTPHTFPHS1.4e-7-----1.1e-104.9e-7---0.018
T82RRTKTPHTFPHSRYM-----------
S90FPHSRYMSQMSVPEQ0.68----0.68-----
S93SRYMSQMSVPEQAEL-0.2-4.4e-9-0.14--0.1-4.4e-34.6e-8--2.1e-12-0.084
S110LKQRINFSDLDQRSI3.9e-11--6.4e-5--3.0e-47.4e-101.7e-7--2.7e-3
Showing 1 to 10 of 129 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

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

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.