Protein: ENSP00000333568
Gene: PRKD1

LinkedOmicsKB © 2022-2023 Zhang Lab

PRKD1:
protein kinase D1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S205GVRRRRLSNVSLTGV101506106-103809710099-1035810395106978218105439318
S208RRRLSNVSLTGVSTI105278-16149710028-18114844312822414539-
S218GVSTIRTSSAELSTS94579-4838--46-10668633631812085114
S219VSTIRTSSAELSTSA101261122-9076353799-8952948678745512105449518
S225SSAELSTSAPDEPLL5156--1212--72---191798----52
S235DEPLLQKSPSESFIG6249--33--90---494697214--125
S237PLLQKSPSESFIGRE1079442-44433882-19973685753611687378318
S247FIGREKRSNSQSYIG47918-219612----------103--
S249GREKRSNSQSYIGRP101432105-10380605699-10862108991101018319105447218
S251EKRSNSQSYIGRPIH18------8-------------
Showing 1 to 10 of 25 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S205GVRRRRLSNVSLTGV-1.5e-26--6e-7-9.0e-6--5.2e-9-3.2e-18-1.2e-40.660.13-1.8e-5
S208RRRLSNVSLTGVSTI0.65---0.28--0.580.19---
S218GVSTIRTSSAELSTS-0.033--1.3e-8---8.3e-60.56---2.8e-4
S219VSTIRTSSAELSTSA-2.5e-22--5.4e-250.27--2.6e-6-9.5e-14-3.9e-8-0.0393.7e-12-3.4e-8
S225SSAELSTSAPDEPLL-----------
S235DEPLLQKSPSESFIG-7.9e-15------7.9e-15----
S237PLLQKSPSESFIGRE0.068--5.5e-5--0.24-2.6e-4-0.941.1e-11-1.4e-4
S247FIGREKRSNSQSYIG-----------
S249GREKRSNSQSYIGRP-2e-12--0.25-0.065--0.1-1.2e-16-9.9e-60.160.092-1.3e-8
S251EKRSNSQSYIGRPIH-----------
Showing 1 to 10 of 25 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationCCRCCS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationCOADS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationGBMS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationHNSCCS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationLSCCS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationLUADS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationOVS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationPDACS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylationUCECS205S208S218S219S225S235S237S247S249S251Y252S332S337S345S420S421T458S460S473S548S549T552S892T894S910proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.