MX2: MX dynamin like GTPase 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4whj chain A
4whj chain B
4x0r chain A
4x0r chain B
5uot chain 0
5uot chain 1
5uot chain 2
5uot chain 3
5uot chain 4
5uot chain 5
5uot chain 6
5uot chain 7
5uot chain 8
5uot chain 9
5uot chain A
5uot chain B
5uot chain C
5uot chain D
5uot chain E
5uot chain F
5uot chain G
5uot chain H
5uot chain I
5uot chain J
5uot chain K
5uot chain L
5uot chain M
5uot chain N
5uot chain O
5uot chain P
5uot chain Q
5uot chain R
5uot chain S
5uot chain T
5uot chain U
5uot chain V
5uot chain W
5uot chain X
5uot chain Y
5uot chain Z
5uot chain a
5uot chain b
5uot chain c
5uot chain d
5uot chain e
5uot chain f
5uot chain g
5uot chain h
5uot chain i
5uot chain j
5uot chain k
5uot chain l
5uot chain m
5uot chain n
5uot chain o
5uot chain p
5uot chain q
5uot chain r
5uot chain s
5uot chain t
5uot chain u
5uot chain v
5uot chain w
5uot chain x
5uot chain y
5uot chain z
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S14 PWPYRRRS QFSSRKY 6 554 - - 69 51 - - 9 - 95 54 29 25 40 36 - - 105 41 - - T258 KYIQRQQT INLVVVP 3 44 - - - - - - - - 10 8 4 4 10 8 - - - - - - S338 QEITNRLS LAEATKK 2 39 - - - - - - - - - - - - 18 15 - - 5 1 - - T602 EIFNPLGT PSQNMKL 7 413 18 - 8 5 - - - - 82 45 39 35 35 31 - - 76 30 7 2 Y675 ILQEKNRY SWLLQEQ 1 6 - - - - - - - - - - - - - - - - 5 1 - - S676 LQEKNRYS WLLQEQS 8 335 17 - - - - - 44 - 58 35 15 13 14 13 7 1 73 33 12 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S14 PWPYRRRS QFSSRKY 2.8e-25 - 1.6e-7 - - 3.3e-6 0.032 4.5e-6 - 4.1e-11 - T258 KYIQRQQT INLVVVP - - - - - - - - - - - S338 QEITNRLS LAEATKK - - - - - - - - - - - T602 EIFNPLGT PSQNMKL 1.3e-5 - - - - 0.096 -0.48 9.5e-6 - 8.1e-4 - Y675 ILQEKNRY SWLLQEQ - - - - - - - - - - - S676 LQEKNRYS WLLQEQS 5.1e-17 - - - - 2.2e-6 - - - 1.1e-12 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S14
T258
S338
T602
Y675
S676
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation CCRCC S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation COAD S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation GBM S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation HNSCC S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation LSCC S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation LUAD S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation OV S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation PDAC S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation UCEC S14 T258 S338 T602 Y675 S676 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S14
T258
S338
T602
Y675
S676
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S14
T258
S338
T602
Y675
S676
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.