C2CD5: C2 calcium dependent domain containing 5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S140 DLNRFRQS SCGVKFF 1 33 - - 17 16 - - - - - - - - - - - - - - - - S250 CTLDKLSS PAAFLPA 10 1189 99 - 95 80 29 25 90 - 77 47 108 99 93 84 34 8 75 33 95 18 S260 AFLPACNS PSKEMKE 10 1544 122 - 103 80 97 100 99 - 108 62 103 95 110 101 83 19 105 44 95 18 T278 NEDPNPNT HSSGPST 10 484 106 - 55 44 7 11 9 - 33 18 30 27 48 45 21 4 8 4 14 - S280 DPNPNTHS SGPSTPL 10 333 74 - 4 4 16 20 63 - 6 4 4 4 14 12 48 9 23 12 11 5 S281 PNPNTHSS GPSTPLK 10 569 65 - 24 21 19 17 37 - 64 38 44 41 38 32 13 4 39 14 55 4 S284 NTHSSGPS TPLKNQT 8 243 6 - - - 9 9 27 - 29 18 - - 5 4 21 4 57 26 22 6 T285 THSSGPST PLKNQTY 7 264 8 - - - 37 26 62 - - - - - 15 12 51 10 6 3 23 11 S293 PLKNQTYS FSPSKSY 6 184 33 - 8 7 - - 8 - - - 49 46 13 12 - - - - 6 2 S295 KNQTYSFS PSKSYSR 10 1299 73 - 66 52 76 76 91 - 103 59 98 90 93 84 61 15 105 44 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S140 DLNRFRQS SCGVKFF - - - - - - - - - - - S250 CTLDKLSS PAAFLPA 4.8e-3 - -2.1e-14 -0.78 - -0.41 2.1e-5 0.006 - 7.4e-12 0.018 S260 AFLPACNS PSKEMKE -1.5e-34 - 0.003 -7.0e-4 - -2.6e-14 -7.5e-17 -4e-11 -0.048 -4.3e-9 -1.2e-4 T278 NEDPNPNT HSSGPST -0.7 - -9.0e-6 - - 0.11 0.013 0.25 - - - S280 DPNPNTHS SGPSTPL 0.2 - - - - - - - - 0.2 - S281 PNPNTHSS GPSTPLK 0.079 - 0.83 - - 0.78 0.32 -0.13 - 7.8e-5 - S284 NTHSSGPS TPLKNQT 0.1 - - - - -0.82 - - - 0.011 - T285 THSSGPST PLKNQTY 0.37 - - -0.58 - - - - 8.3e-3 - -0.59 S293 PLKNQTYS FSPSKSY -6.8e-16 - - - - - -6.7e-16 - - - - S295 KNQTYSFS PSKSYSR -2.4e-8 - 2.0e-5 0.24 - -5.8e-4 -1.7e-11 -2e-10 -0.86 -4.8e-3 -0.095
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S140
S250
S260
T278
S280
S281
S284
T285
S293
S295
S297
S299
S301
S304
S305
S306
S307
T309
T314
T317
S321
S323
T339
T601
S606
Y607
S637
S643
S657
S659
S661
S662
T666
S671
T807
S817
T818
S832
S852
S991
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation CCRCC S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation COAD S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation GBM S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation HNSCC S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation LSCC S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation LUAD S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation OV S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation PDAC S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation UCEC S140 S250 S260 T278 S280 S281 S284 T285 S293 S295 S297 S299 S301 S304 S305 S306 S307 T309 T314 T317 S321 S323 T339 T601 S606 Y607 S637 S643 S657 S659 S661 S662 T666 S671 T807 S817 T818 S832 S852 S991 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S140
S250
S260
T278
S280
S281
S284
T285
S293
S295
S297
S299
S301
S304
S305
S306
S307
T309
T314
T317
S321
S323
T339
T601
S606
Y607
S637
S643
S657
S659
S661
S662
T666
S671
T807
S817
T818
S832
S852
S991
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S140
S250
S260
T278
S280
S281
S284
T285
S293
S295
S297
S299
S301
S304
S305
S306
S307
T309
T314
T317
S321
S323
T339
T601
S606
Y607
S637
S643
S657
S659
S661
S662
T666
S671
T807
S817
T818
S832
S852
S991
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.