C2CD3: C2 domain containing 3 centriole elongation regulator
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S230 KELAANSS RSTTPRG 2 55 - - - - - - - - - - 15 14 13 13 - - - - - - S260 SSFGLQHS LNSGQSL 4 72 - - - - - - 37 - 6 3 10 9 4 3 - - - - - - S263 GLQHSLNS GQSLESV 1 8 - - - - - - - - - - 4 4 - - - - - - - - S282 RAPRKQMS LLNSSEF 3 118 - - - - - - 18 - - - 25 24 - - - - - - 47 4 S301 RTVAKSHS DSCILSS 6 383 - - - - - - 63 - 23 15 24 20 72 65 - - 5 1 77 18 S338 MVISAMKS SPETSML 1 8 - - - - - - - - - - - - 4 4 - - - - - - S339 VISAMKSS PETSMLL 3 96 - - - - - - - - - - 15 14 13 11 - - - - 41 2 S466 TSISDFLS EEDDIVP 7 358 - - 17 16 - - 26 - 15 9 74 67 53 47 - - 4 1 20 9 S554 TMGVPPDS PQMTPGK 7 309 - - 48 30 - - 18 - 20 14 20 17 35 33 - - 3 2 51 18 T727 YTPLCAPT SPNKALP 4 91 - - - - - - 8 - 28 18 10 10 9 8 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S230 KELAANSS RSTTPRG - - - - - - - - - - - S260 SSFGLQHS LNSGQSL - - - - - - - - - - - S263 GLQHSLNS GQSLESV - - - - - - - - - - - S282 RAPRKQMS LLNSSEF -0.46 - - - - - -0.46 - - - - S301 RTVAKSHS DSCILSS 8.5e-8 - - - - 1.9e-3 0.1 5.7e-7 - - 0.34 S338 MVISAMKS SPETSML - - - - - - - - - - - S339 VISAMKSS PETSMLL - - - - - - - - - - - S466 TSISDFLS EEDDIVP 0.038 - - - - - 0.2 0.097 - - - S554 TMGVPPDS PQMTPGK 0.01 - 0.037 - - 0.26 -0.27 -0.97 - - 2.3e-4 T727 YTPLCAPT SPNKALP 0.098 - - - - 0.098 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S230
S260
S263
S282
S301
S338
S339
S466
S554
T727
S728
S976
S1312
Y1316
S1606
S1638
S1648
S1829
T1873
S1874
S1891
S2018
S2020
S2037
S2049
S2050
Y2059
S2060
S2085
S2099
S2114
S2131
S2132
S2146
S2148
S2150
S2194
S2216
S2221
S2224
S2328
S2350
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation CCRCC S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation COAD S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation GBM S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation HNSCC S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation LSCC S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation LUAD S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation OV S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation PDAC S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation UCEC S230 S260 S263 S282 S301 S338 S339 S466 S554 T727 S728 S976 S1312 Y1316 S1606 S1638 S1648 S1829 T1873 S1874 S1891 S2018 S2020 S2049 S2050 Y2059 S2060 S2085 S2099 S2114 S2131 S2132 S2146 S2148 S2150 S2194 S2216 S2221 S2224 S2328 S2350 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S230
S260
S263
S282
S301
S338
S339
S466
S554
T727
S728
S976
S1312
Y1316
S1606
S1638
S1648
S1829
T1873
S1874
S1891
S2018
S2020
S2037
S2049
S2050
Y2059
S2060
S2085
S2099
S2114
S2131
S2132
S2146
S2148
S2150
S2194
S2216
S2221
S2224
S2328
S2350
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S230
S260
S263
S282
S301
S338
S339
S466
S554
T727
S728
S976
S1312
Y1316
S1606
S1638
S1648
S1829
T1873
S1874
S1891
S2018
S2020
S2037
S2049
S2050
Y2059
S2060
S2085
S2099
S2114
S2131
S2132
S2146
S2148
S2150
S2194
S2216
S2221
S2224
S2328
S2350
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.