PDCD1: programmed cell death 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2m2d chain A
3rrq chain A
4zqk chain B
5b8c chain C
5b8c chain F
5b8c chain I
5b8c chain L
5ggr chain Y
5ggr chain Z
5ggs chain Y
5ggs chain Z
5ius chain A
5ius chain B
5jxe chain A
5jxe chain B
5wt9 chain G
6hig chain B
6j14 chain G
6j15 chain C
6j15 chain D
6jbt chain F
6jjp chain C
6jjp chain F
6k0y chain C
6r5g chain B
6roy chain C
6roy chain D
6roz chain B
6roz chain D
6umt chain A
6umu chain A
6umv chain A
6xkr chain P
7bxa chain A
7bxa chain P
7cgw chain C
7cgw chain P
7cu5 chain E
7cu5 chain Q
7e9b chain C
7vux chain A
7wsl chain D
7wvm chain E
7wvm chain F
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T234 DFQWREKT PEPPVPC 6 264 - - 7 7 4 5 - - 17 11 64 56 44 41 6 2 - - - - S255 YATIVFPS GMGTSSP 1 8 - - - - - - - - - - - - 4 4 - - - - - - S261 PSGMGTSS PARRGSA 1 17 - - - - - - - - - - - - - - - - - - 13 4 S267 SSPARRGS ADGPRSA 6 226 - - - - - - 18 - - - 39 35 17 13 28 4 27 12 18 15 S285 RPEDGHCS WPL____ 10 942 88 - 53 42 39 33 9 - 108 62 93 86 74 69 34 8 70 28 37 9
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T234 DFQWREKT PEPPVPC -0.028 - - - - - -0.44 -0.02 - - - S255 YATIVFPS GMGTSSP - - - - - - - - - - - S261 PSGMGTSS PARRGSA - - - - - - - - - - - S267 SSPARRGS ADGPRSA -0.75 - - - - - 0.31 - - -0.14 - S285 RPEDGHCS WPL____ 0.001 - 4.6e-10 -0.78 - 0.72 0.011 0.35 - -0.082 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T234
S255
S261
S267
S285
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T234 S255 S261 S267 S285 protein RNA SCNV methylation CCRCC T234 S255 S261 S267 S285 protein RNA SCNV methylation COAD T234 S255 S261 S267 S285 protein RNA SCNV methylation GBM T234 S255 S261 S267 S285 protein RNA SCNV methylation HNSCC T234 S255 S261 S267 S285 protein RNA SCNV methylation LSCC T234 S255 S261 S267 S285 protein RNA SCNV methylation LUAD T234 S255 S261 S267 S285 protein RNA SCNV methylation OV T234 S255 S261 S267 S285 protein RNA SCNV methylation PDAC T234 S255 S261 S267 S285 protein RNA SCNV methylation UCEC T234 S255 S261 S267 S285 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T234
S255
S261
S267
S285
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T234
S255
S261
S267
S285
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.