FGG: fibrinogen gamma chain
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1dug chain A
1dug chain B
1fib chain A
1fic chain A
1fic chain B
1fid chain A
1fza chain C
1fza chain F
1fzb chain C
1fzb chain F
1fzc chain C
1fzc chain F
1fze chain C
1fze chain F
1fzf chain C
1fzf chain F
1fzg chain C
1fzg chain F
1lt9 chain C
1lt9 chain F
1ltj chain C
1ltj chain F
1n86 chain C
1n86 chain F
1n8e chain C
1n8e chain F
1re3 chain C
1re3 chain F
1re4 chain C
1re4 chain F
1rf0 chain C
1rf0 chain F
1rf1 chain C
1rf1 chain F
2a45 chain I
2a45 chain L
2ffd chain C
2ffd chain F
2fib chain A
2h43 chain C
2h43 chain F
2hlo chain C
2hlo chain F
2hod chain C
2hod chain F
2hod chain I
2hod chain L
2hpc chain C
2hpc chain F
2hpc chain I
2hpc chain L
2hwl chain P
2oyh chain C
2oyh chain F
2oyi chain C
2oyi chain F
2q9i chain C
2q9i chain F
2vdo chain C
2vdp chain C
2vdq chain C
2vdr chain C
2vr3 chain C
2vr3 chain D
2xnx chain C
2xnx chain F
2xnx chain I
2xnx chain L
2xny chain C
2xny chain F
2y7l chain B
2z4e chain C
2z4e chain F
3bvh chain C
3bvh chain F
3e1i chain C
3e1i chain F
3fib chain A
3ghg chain C
3ghg chain F
3ghg chain I
3ghg chain L
3h32 chain C
3h32 chain F
3hus chain C
3hus chain F
4b60 chain C
4b60 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T80 LHQVENKT SEVKQLI 7 223 - - 16 15 - - 10 - 67 39 29 26 4 4 - - 4 1 8 - S81 HQVENKTS EVKQLIK 7 125 - - 16 15 - - 10 - 5 3 29 26 4 4 - - 4 1 8 - S99 LTYNPDES SKPNMID 1 7 - - 4 3 - - - - - - - - - - - - - - - - S227 FQKRLDGS VDFKKNW 1 8 - - - - - - - - - - - - - - 7 1 - - - - T247 GFGHLSPT GTTEFWL 1 9 - - - - - - - - 7 2 - - - - - - - - - - S332 PSDKFFTS HNGMQFS 1 9 - - - - - - - - 5 4 - - - - - - - - - - T385 GTYSKAST PNGYDNG 6 321 - - 17 8 - - - - 73 43 58 53 28 24 - - 6 3 6 2 Y389 KASTPNGY DNGIIWA 1 10 - - - - - - - - - - 5 5 - - - - - - - - Y444 EHPAETEY DSLYPED 4 192 17 - 37 26 - - - - 25 12 39 36 - - - - - - - - S446 PAETEYDS LYPEDDL 4 392 40 - 62 50 - - - - 61 35 74 70 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T80 LHQVENKT SEVKQLI -1.2e-5 - - - - -0.12 -3.8e-6 - - - - S81 HQVENKTS EVKQLIK -3.8e-6 - - - - - -3.8e-6 - - - - S99 LTYNPDES SKPNMID - - - - - - - - - - - S227 FQKRLDGS VDFKKNW - - - - - - - - - - - T247 GFGHLSPT GTTEFWL - - - - - - - - - - - S332 PSDKFFTS HNGMQFS - - - - - - - - - - - T385 GTYSKAST PNGYDNG -2.6e-10 - - - - -0.096 -2.5e-9 -9.0e-4 - - - Y389 KASTPNGY DNGIIWA - - - - - - - - - - - Y444 EHPAETEY DSLYPED -0.65 - -0.042 - - 6.2e-3 -0.14 - - - - S446 PAETEYDS LYPEDDL -4.8e-3 - -2.9e-3 - - 0.032 -5.0e-5 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T80
S81
S99
S227
T247
S332
T385
Y389
Y444
S446
Y448
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation CCRCC T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation COAD T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation GBM T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation HNSCC T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation LSCC T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation LUAD T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation OV T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation PDAC T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation UCEC T80 S81 S99 S227 T247 S332 T385 Y389 Y444 S446 Y448 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T80
S81
S99
S227
T247
S332
T385
Y389
Y444
S446
Y448
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T80
S81
S99
S227
T247
S332
T385
Y389
Y444
S446
Y448
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.