CENPA: centromere protein A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3an2 chain A
3an2 chain E
3nqj chain A
3nqu chain A
3r45 chain A
3wtp chain A
5cvd chain D
5cvd chain E
5z23 chain A
5z23 chain E
5zbx chain A
5zbx chain E
6buz chain A
6buz chain E
6c0w chain A
6c0w chain E
6e0c chain A
6e0c chain E
6e0p chain A
6e0p chain E
6kdq chain E
6kdq chain F
6kds chain E
6l49 chain A
6l49 chain E
6muo chain A
6muo chain E
6mup chain A
6mup chain E
6o1d chain A
6o1d chain E
6se0 chain A
6se0 chain E
6se6 chain A
6se6 chain E
6see chain A
6see chain E
6sef chain A
6sef chain E
6seg chain A
6seg chain E
6tem chain A
6tem chain E
7d20 chain A
7d20 chain E
7pii chain A
7pii chain E
7r5r chain A
7r5r chain E
7u46 chain A
7u46 chain E
7u47 chain A
7u47 chain E
7u47 chain L
7u47 chain P
7u4d chain A
7u4d chain E
7u4d chain L
7u4d chain P
7ywx chain A
7ywx chain E
7yyh chain A
7yyh chain E
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S7 _MGPRRRS RKPEAPR 1 30 - - - - - - - - - - - - - - - - 20 10 - - S17 PEAPRRRS PSPTPTP 10 509 22 - 4 4 64 70 37 - 38 22 59 53 18 12 40 7 19 8 19 13 S19 APRRRSPS PTPTPGP 10 735 8 - 91 66 87 83 37 - 21 14 5 5 8 8 76 17 105 42 48 14 T21 RRRSPSPT PTPGPSR 2 23 - - - - 5 4 - - - - - - - - - - - - 11 3 T23 RSPSPTPT PGPSRRG 1 7 - - - - - - - - - - - - - - - - - - 7 - S32 GPSRRGPS LGASSHQ 4 182 9 - - - 40 41 36 - 37 19 - - - - - - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S7 _MGPRRRS RKPEAPR -0.5 - - - - - - - - -0.5 - S17 PEAPRRRS PSPTPTP 4.8e-30 - - 2.5e-19 - 8.8e-6 3.1e-10 - - - - S19 APRRRSPS PTPTPGP 4.3e-23 - 6.5e-23 6.6e-16 - -0.5 - - 6.4e-4 5.1e-11 -2.8e-3 T21 RRRSPSPT PTPGPSR - - - - - - - - - - - T23 RSPSPTPT PGPSRRG - - - - - - - - - - - S32 GPSRRGPS LGASSHQ 5.3e-9 - - 1.9e-10 - 0.059 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S7
S17
S19
T21
T23
S32
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation CCRCC S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation COAD S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation GBM S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation HNSCC S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation LSCC S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation LUAD S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation OV S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation PDAC S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation UCEC S7 S17 S19 T21 T23 S32 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S7
S17
S19
T21
T23
S32
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S7
S17
S19
T21
T23
S32
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.