Protein: ENSP00000337194
Gene: PRPF4B

LinkedOmicsKB © 2022-2023 Zhang Lab

PRPF4B:
pre-mRNA processing factor 4B

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S20PEMEDANSEKSINEE101544122-10380949499-10862108991101018319105449518
S23EDANSEKSINEENGE10117557-907681099-92529385101934611105449518
S32NEENGEVSEDQSQNK10129987-9580838772-874793868979691594398413
S36GEVSEDQSQNKHSRH10102571-99765418-1086210395106971539941185
S60KHKKHKHSSEEDKDK514128-86--35---2926-------9
S61HKKHKHSSEEDKDKK614828-86--35---2926----52-9
S87RKEIIDASDKEGMSP10131096-9370808190-1025810893102837199428718
S93ASDKEGMSPAKRTKL101535122-10380889199-10862108991101018319105449518
Y140MGLILQGYESGSEEE924115-8-261927-442020171312--52112
S142LILQGYESGSEEEGE1066543-33324581-663278696762226156377
Showing 1 to 10 of 65 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S20PEMEDANSEKSINEE4e-19--2.4e-247.9e-14-1.3e-96.9e-315.7e-250.29-2e-143.2e-6
S23EDANSEKSINEENGE2.9e-5--1.2e-19--8.8e-63.6e-201.2e-20-0.82-2.6e-124.1e-4
S32NEENGEVSEDQSQNK1.4e-11--1.5e-225.7e-9-3.7e-63.6e-242.5e-15-0.086-6.4e-56.3e-6
S36GEVSEDQSQNKHSRH4.7e-11--4.2e-20--6.2e-133.7e-279.5e-28--2.2e-9-
S60KHKKHKHSSEEDKDK-0.97------0.97----
S61HKKHKHSSEEDKDKK-0.97------0.97----
S87RKEIIDASDKEGMSP0.56--0.160.18-0.370.160.54--0.21-0.98
S93ASDKEGMSPAKRTKL7.1e-5--1.3e-110.45-6.0e-65.1e-143e-81.7e-3-9.2e-132.6e-4
Y140MGLILQGYESGSEEE2.0e-6--2.4e-6-0.150.039----
S142LILQGYESGSEEEGE9.7e-9--9.0e-5--0.0824.7e-163.2e-8---
Showing 1 to 10 of 65 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationCCRCCS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationCOADS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationGBMS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationHNSCCS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationLSCCS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationLUADS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationOVS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationPDACS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylationUCECS20S23S32S36S60S61S87S93Y140S142S144S166S201S232S239S241S257S277S283S285S292S294S328S330S335S341S349S354S356S366S368S381S383T385S387S394S396S427S431S437T439S443S445S507S509S518S519S520S562S565S568S569S572S573T576S578S580S606S622S623T634S636S837S839Y849proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.