PLCB1: phospholipase C beta 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S283 EKYEPNNS LARKGQI 2 62 - - - - - - 54 - - - - - - - - - - - 6 2 S308 GEENGVVS PEKLDLN 1 90 - - - - - - 90 - - - - - - - - - - - - - S410 SPFPILLS FENHVDS 1 16 - - 8 8 - - - - - - - - - - - - - - - - S417 SFENHVDS PKQQAKM 1 98 - - - - - - 98 - - - - - - - - - - - - - S494 SNTYSDSS SMFEPSS 2 70 - - - - - - 32 - - - 20 18 - - - - - - - - S495 NTYSDSSS MFEPSSP 3 94 - - 12 12 - - 32 - - - 20 18 - - - - - - - - S500 SSSMFEPS SPGAGEA 2 32 - - 12 12 - - 8 - - - - - - - - - - - - - S501 SSMFEPSS PGAGEAD 1 27 - - - - - - 27 - - - - - - - - - - - - - T509 PGAGEADT ESDDDDD 5 46 - - - - - - 7 - - - 4 4 4 4 - - 5 4 14 - S511 AGEADTES DDDDDDD 7 111 - - 8 8 - - 38 - 7 2 4 4 4 3 - - 4 2 25 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S283 EKYEPNNS LARKGQI - - - - - - - - - - - S308 GEENGVVS PEKLDLN - - - - - - - - - - - S410 SPFPILLS FENHVDS - - - - - - - - - - - S417 SFENHVDS PKQQAKM - - - - - - - - - - - S494 SNTYSDSS SMFEPSS -0.072 - - - - - -0.072 - - - - S495 NTYSDSSS MFEPSSP -0.072 - - - - - -0.072 - - - - S500 SSSMFEPS SPGAGEA - - - - - - - - - - - S501 SSMFEPSS PGAGEAD - - - - - - - - - - - T509 PGAGEADT ESDDDDD - - - - - - - - - - - S511 AGEADTES DDDDDDD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S283
S308
S410
S417
S494
S495
S500
S501
T509
S511
S524
S564
S569
S582
T847
S849
S853
T858
S887
S978
S982
S1177
S1181
S1188
T1197
S1199
S1200
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation CCRCC S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation COAD S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation GBM S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation HNSCC S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation LSCC S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation LUAD S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation OV S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation PDAC S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation UCEC S283 S308 S410 S417 S494 S495 S500 S501 T509 S511 S524 S564 S569 S582 T847 S849 S853 T858 S887 S978 S982 S1177 S1181 S1188 T1197 S1199 S1200 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S283
S308
S410
S417
S494
S495
S500
S501
T509
S511
S524
S564
S569
S582
T847
S849
S853
T858
S887
S978
S982
S1177
S1181
S1188
T1197
S1199
S1200
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S283
S308
S410
S417
S494
S495
S500
S501
T509
S511
S524
S564
S569
S582
T847
S849
S853
T858
S887
S978
S982
S1177
S1181
S1188
T1197
S1199
S1200
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.