Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4qmg chain F
4qmg chain G
4qmg chain H
4qmg chain I
4qmg chain J
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S111 ALLKNLRS EEQKKKN 10 485 30 - 34 31 16 20 72 - 27 17 34 31 19 17 60 16 7 3 33 18 T143 AEGEAVRT PQSVTAK 9 166 18 - 29 20 8 10 - - 5 4 4 4 12 11 14 3 2 1 12 9 S146 EAVRTPQS VTAKQPP 7 282 9 - - - 13 14 - - 24 11 35 32 21 20 - - 70 28 5 - T148 VRTPQSVT AKQPPEI 6 116 6 - - - 9 9 - - - - 5 4 4 4 - - 21 9 31 14 S179 DAKAVQNS SRHDGKE 1 18 - - - - - - 18 - - - - - - - - - - - - - S180 AKAVQNSS RHDGKEV 1 44 - - - - - - 44 - - - - - - - - - - - - - T212 RKRDKVLT DSGSLDS 5 83 - - 14 12 6 3 9 - - - 9 5 13 12 - - - - - - S214 RDKVLTDS GSLDSTI 9 268 24 - 13 12 34 28 26 - 11 5 30 27 22 18 2 - 12 4 - - S216 KVLTDSGS LDSTIPG 10 753 82 - 36 34 65 61 81 - 56 34 39 35 65 58 25 5 28 15 23 11 S244 TASFPVGS KKNKGDS 1 7 - - - - - - 7 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S111 ALLKNLRS EEQKKKN 2.5e-8 - 0.036 - - 9.6e-3 4.5e-12 - 1.7e-3 - -0.022 T143 AEGEAVRT PQSVTAK 3.9e-7 - 3.9e-7 - - - - - - - - S146 EAVRTPQS VTAKQPP -0.67 - - - - 0.61 6.5e-5 -0.45 - -4.6e-6 - T148 VRTPQSVT AKQPPEI 5.3e-3 - - - - - - - - - 5.3e-3 S179 DAKAVQNS SRHDGKE - - - - - - - - - - - S180 AKAVQNSS RHDGKEV - - - - - - - - - - - T212 RKRDKVLT DSGSLDS - - - - - - - - - - - S214 RDKVLTDS GSLDSTI 2.1e-5 - - -0.39 - - 3.6e-5 4.0e-5 - - - S216 KVLTDSGS LDSTIPG 5.9e-6 - 1.4e-4 -0.22 - 0.092 1e-8 6.1e-12 - -7.9e-3 -0.026 S244 TASFPVGS KKNKGDS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S111
T143
S146
T148
S179
S180
T212
S214
S216
S244
S251
S258
S273
T280
S295
S298
S306
S308
S311
T317
S323
T326
T331
S339
S341
S344
S347
S351
T352
S357
S359
S362
Y364
S369
S415
S426
S457
T458
T462
T477
S478
S494
T495
S496
S506
S525
S529
S534
S562
S565
S568
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation CCRCC S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation COAD S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation GBM S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation HNSCC S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation LSCC S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation LUAD S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation OV S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation PDAC S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation UCEC S111 T143 S146 T148 S179 S180 T212 S214 S216 S244 S251 S258 S273 T280 S295 S298 S306 S308 S311 T317 S323 T326 T331 S339 S341 S344 S347 S351 T352 S357 S359 S362 Y364 S369 S415 S426 S457 T458 T462 T477 S478 S494 T495 S496 S506 S525 S529 S534 S562 S565 S568 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S111
T143
S146
T148
S179
S180
T212
S214
S216
S244
S251
S258
S273
T280
S295
S298
S306
S308
S311
T317
S323
T326
T331
S339
S341
S344
S347
S351
T352
S357
S359
S362
Y364
S369
S415
S426
S457
T458
T462
T477
S478
S494
T495
S496
S506
S525
S529
S534
S562
S565
S568
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S111
T143
S146
T148
S179
S180
T212
S214
S216
S244
S251
S258
S273
T280
S295
S298
S306
S308
S311
T317
S323
T326
T331
S339
S341
S344
S347
S351
T352
S357
S359
S362
Y364
S369
S415
S426
S457
T458
T462
T477
S478
S494
T495
S496
S506
S525
S529
S534
S562
S565
S568
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.