CDC42EP4: CDC42 effector protein 4
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S9 PILKQLVS SSVHSKR 1 9 - - - - - - 9 - - - - - - - - - - - - - S10 ILKQLVSS SVHSKRR 2 17 - - 4 4 - - 9 - - - - - - - - - - - - - S11 LKQLVSSS VHSKRRS 10 1419 107 - 86 72 93 95 99 - 108 62 108 99 94 84 83 19 84 36 72 18 S14 LVSSSVHS KRRSRAD 7 325 - - - - 34 46 81 - - - 48 44 4 4 22 4 16 8 12 2 S18 SVHSKRRS RADLTAE 9 611 14 - - - 86 93 90 - 32 23 48 45 18 16 55 13 11 5 49 13 T23 RRSRADLT AEMISAP 1 16 - - - - - - - - - - - - - - 13 3 - - - - T50 AGDAFGDT SFLNSKA 1 9 - - - - - - - - - - - - 5 4 - - - - - - S51 GDAFGDTS FLNSKAG 3 99 8 - - - - - 55 - - - - - - - - - - - 29 7 S64 AGEPDGES LDEQPSS 10 1497 113 - 103 80 97 100 99 - 108 62 108 99 102 93 63 13 102 42 95 18 S70 ESLDEQPS SSSSKRS 3 32 6 - 4 4 - - - - 12 6 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S9 PILKQLVS SSVHSKR - - - - - - - - - - - S10 ILKQLVSS SVHSKRR - - - - - - - - - - - S11 LKQLVSSS VHSKRRS -3.2e-43 - -0.22 -6.6e-23 - -4.2e-4 -1.1e-24 -4.5e-11 -0.028 -0.37 -8.9e-6 S14 LVSSSVHS KRRSRAD -1e-17 - - -3.6e-8 - - -3.8e-11 - - - - S18 SVHSKRRS RADLTAE -2.2e-37 - - -1.3e-24 - -2.9e-6 -9.6e-15 - -0.21 - -3.2e-6 T23 RRSRADLT AEMISAP - - - - - - - - - - - T50 AGDAFGDT SFLNSKA - - - - - - - - - - - S51 GDAFGDTS FLNSKAG - - - - - - - - - - - S64 AGEPDGES LDEQPSS -9.9e-76 - -0.018 -1.1e-27 - -2.2e-14 -2.4e-27 -1e-25 -0.014 -2.4e-3 -1.3e-5 S70 ESLDEQPS SSSSKRS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S9
S10
S11
S14
S18
T23
T50
S51
S64
S70
S71
S72
S73
S74
S77
S89
S91
S105
S109
S118
S138
S140
S141
S142
T159
S174
T188
S275
S278
S292
S295
S298
S301
S307
S308
S309
S311
S312
T314
S315
S322
S336
S344
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation CCRCC S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation COAD S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation GBM S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation HNSCC S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation LSCC S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation LUAD S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation OV S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation PDAC S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation UCEC S9 S10 S11 S14 S18 T23 T50 S51 S64 S70 S71 S72 S73 S74 S77 S89 S91 S105 S109 S118 S138 S140 S141 S142 T159 S174 T188 S275 S278 S292 S295 S298 S301 S307 S308 S309 S311 S312 T314 S315 S322 S336 S344 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S9
S10
S11
S14
S18
T23
T50
S51
S64
S70
S71
S72
S73
S74
S77
S89
S91
S105
S109
S118
S138
S140
S141
S142
T159
S174
T188
S275
S278
S292
S295
S298
S301
S307
S308
S309
S311
S312
T314
S315
S322
S336
S344
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S9
S10
S11
S14
S18
T23
T50
S51
S64
S70
S71
S72
S73
S74
S77
S89
S91
S105
S109
S118
S138
S140
S141
S142
T159
S174
T188
S275
S278
S292
S295
S298
S301
S307
S308
S309
S311
S312
T314
S315
S322
S336
S344
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.