Protein: ENSP00000338615
Gene: CTBP2

LinkedOmicsKB © 2022-2023 Zhang Lab

CTBP2:
C-terminal binding protein 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S106RVIVRIGSGYDNVDI17------------------52
S365NKEFFVTSAPWSVID965632-6259575019---5853595720560243011
S369FVTSAPWSVIDQQAI1094079-6745656927-985488819889309146129
Y387LNGATYRYPPGIVGV23224-----------------53
T414IPGGIPVTHNLPTVA9714122-58551818--62365955928420415772
T419PVTHNLPTVAHPSQA5506-4445----10944------
S424LPTVAHPSQAPSPNQ8767---729-7310844--528-
S428AHPSQAPSPNQPTKH103939-43513999-231413131512131228495
Showing 1 to 8 of 8 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S106RVIVRIGSGYDNVDI-----------
S365NKEFFVTSAPWSVID-0.42-0.860.5---3.1e-4-0.52-0.210.85
S369FVTSAPWSVIDQQAI-3.3e-5--0.844.2e-4--4.9e-4-2.6e-8-3.9e-4---
Y387LNGATYRYPPGIVGV-----------
T414IPGGIPVTHNLPTVA-0.011-0.67---0.035-0.07-0.11---
T419PVTHNLPTVAHPSQA-----------
S424LPTVAHPSQAPSPNQ-----------
S428AHPSQAPSPNQPTKH-0.86--0.29--0.19-----
Showing 1 to 8 of 8 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationCCRCCS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationCOADS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationGBMS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationHNSCCS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationLSCCS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationLUADS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationOVS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationPDACS106S365S369Y387T414T419S424S428proteinRNASCNVmethylationUCECS106S365S369Y387T414T419S424S428proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.