ANAPC1: anaphase promoting complex subunit 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4ui9 chain A
5a31 chain A
5g04 chain A
5g05 chain A
5khr chain A
5khu chain A
5l9t chain A
5l9u chain A
5lcw chain A
5lgg chain A
6q6g chain A
6q6h chain A
6tlj chain A
6tm5 chain A
6tnt chain A
7qe7 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S50 QPASELWS SDGAAGL 2 31 15 - 8 8 - - - - - - - - - - - - - - - - S51 PASELWSS DGAAGLV 9 391 23 - 23 21 25 20 35 - 46 30 40 36 34 33 - - 15 6 4 - S60 GAAGLVGS LQEVTIH 7 264 23 - 4 4 15 12 - - 40 21 30 27 37 32 - - - - 19 - S202 SHEVPPGS PREPLPT 1 64 - - - - - - - - - - - - - - 52 12 - - - - S333 HSQSRSTS SPSLHSR 3 94 - - - - 9 9 18 - - - - - - - 50 8 - - - - S334 SQSRSTSS PSLHSRS 1 52 - - - - - - - - - - - - - - 43 9 - - - - S341 SPSLHSRS PSISNMA 2 35 - - - - - - - - - - - - 4 4 - - - - 25 2 S343 SLHSRSPS ISNMAAL 8 570 - - 8 - 37 34 81 - 11 7 58 53 - - 57 12 68 31 95 18 S345 HSRSPSIS NMAALSR 3 25 - - - - - - 9 - - - - - 4 4 6 2 - - - - S355 AALSRAHS PALGVHS 8 249 17 - - - 12 15 46 - - - 29 27 8 7 34 9 19 11 13 2
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S50 QPASELWS SDGAAGL - - - - - - - - - - - S51 PASELWSS DGAAGLV 1.3e-7 - 5.1e-5 6.8e-6 - 0.11 0.002 -0.16 - - - S60 GAAGLVGS LQEVTIH 0.056 - - - - -0.082 9.4e-4 0.082 - - - S202 SHEVPPGS PREPLPT 0.4 - - - - - - - 0.4 - - S333 HSQSRSTS SPSLHSR - - - - - - - - - - - S334 SQSRSTSS PSLHSRS - - - - - - - - - - - S341 SPSLHSRS PSISNMA - - - - - - - - - - - S343 SLHSRSPS ISNMAAL 1.2e-4 - - -8.6e-3 - - 2.1e-10 - 0.51 1.4e-8 -0.15 S345 HSRSPSIS NMAALSR - - - - - - - - - - - S355 AALSRAHS PALGVHS 1.2e-5 - - - - - 1.2e-5 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S50
S51
S60
S202
S333
S334
S341
S343
S345
S355
S377
S386
T400
S518
T520
T524
S529
T530
S536
T537
S547
S555
S563
S569
S686
S688
S699
S703
S727
S731
S733
S916
S1058
S1347
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation CCRCC S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation COAD S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation GBM S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation HNSCC S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation LSCC S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation LUAD S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation OV S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation PDAC S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation UCEC S50 S51 S60 S202 S333 S334 S341 S343 S345 S355 S377 S386 T400 S518 T520 T524 S529 T530 S536 T537 S547 S555 S563 S569 S686 S688 S699 S703 S727 S731 S733 S916 S1058 S1347 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S50
S51
S60
S202
S333
S334
S341
S343
S345
S355
S377
S386
T400
S518
T520
T524
S529
T530
S536
T537
S547
S555
S563
S569
S686
S688
S699
S703
S727
S731
S733
S916
S1058
S1347
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S50
S51
S60
S202
S333
S334
S341
S343
S345
S355
S377
S386
T400
S518
T520
T524
S529
T530
S536
T537
S547
S555
S563
S569
S686
S688
S699
S703
S727
S731
S733
S916
S1058
S1347
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.