Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1n11 chain A
2yqf chain A
2yvi chain A
3f59 chain A
3f59 chain B
3f59 chain C
3f59 chain D
3kbt chain C
3kbt chain D
3kbu chain C
3kbu chain D
3ud1 chain A
3ud1 chain B
3ud1 chain C
3ud2 chain A
3ud2 chain B
3ud2 chain C
7tw3 chain G
7tw5 chain G
7tw5 chain H
7tw6 chain G
7uzq chain J
7uzu chain A
7v0k chain H
7v0m chain A
7v0s chain J
7v0x chain J
8cs9 chain A
8csl chain A
8csv chain A
8cte chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S4 ____MPYS VGFREAD 8 786 - - 76 55 58 67 72 - 54 29 78 72 62 57 - - 32 13 54 7 S15 READAATS FLRAARS 4 98 - - 8 8 - - 8 - - - 30 28 8 8 - - - - - - S429 NLLQRGAS PNVSNVK 7 726 - - 40 27 - - 99 - 85 49 75 69 60 53 - - 56 26 71 16 S594 LLLPRGGS PHSPAWN 2 93 - - - - - - 55 - - - 20 18 - - - - - - - - S597 PRGGSPHS PAWNGYT 5 279 - - - - - - 82 - 28 17 43 40 32 28 - - - - - 9 Y735 NAKTKLGY SPLHQAA 2 28 - - - - - - 19 - - - 4 5 - - - - - - - - S736 AKTKLGYS PLHQAAQ 5 69 - - 5 4 - - 26 - 5 2 10 9 4 4 - - - - - - S759 LLLKNGAS PNEVSSD 7 617 - - 31 27 - - 90 - 25 18 98 90 83 77 - - 16 7 44 11 S764 GASPNEVS SDGTTPL 1 8 - - - - - - - - - - 4 4 - - - - - - - - S765 ASPNEVSS DGTTPLA 3 46 - - 5 4 - - - - - - 15 14 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S4 ____MPYS VGFREAD -3.8e-20 - 1.1e-9 -1.2e-12 - -1.2e-7 -2.5e-23 -5.8e-17 - 0.035 - S15 READAATS FLRAARS -3.7e-11 - - - - - -3.7e-11 - - - - S429 NLLQRGAS PNVSNVK -2.7e-25 - 2.7e-5 - - -1.1e-8 -1.6e-22 -1.2e-17 - -4.1e-4 -0.037 S594 LLLPRGGS PHSPAWN -1.6e-8 - - - - - -1.6e-8 - - - - S597 PRGGSPHS PAWNGYT -2.5e-28 - - - - -9.9e-5 -1.8e-14 -4e-14 - - - Y735 NAKTKLGY SPLHQAA - - - - - - - - - - - S736 AKTKLGYS PLHQAAQ - - - - - - - - - - - S759 LLLKNGAS PNEVSSD -1e-23 - 0.011 - - -8.4e-3 -2.1e-28 -9.7e-25 - - -0.3 S764 GASPNEVS SDGTTPL - - - - - - - - - - - S765 ASPNEVSS DGTTPLA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S4
S15
S429
S594
S597
Y735
S736
S759
S764
S765
T769
S781
T783
S805
S817
S826
S834
S856
S881
T896
S903
S907
T961
S1042
Y1073
T1075
S1082
S1312
T1378
T1380
T1393
S1396
S1428
S1490
S1505
S1507
S1509
S1593
T1596
S1607
S1628
T1631
T1660
S1666
S1671
S1674
S1686
T1688
S1690
T1693
S1696
T1878
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation CCRCC S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation COAD S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation GBM S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation HNSCC S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation LSCC S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation LUAD S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation OV S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation PDAC S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation UCEC S4 S15 S429 S594 S597 Y735 S736 S759 S764 S765 T769 S781 T783 S805 S817 S826 S834 S856 T896 S903 S907 T961 S1042 Y1073 T1075 S1082 S1312 T1378 T1380 T1393 S1396 S1428 S1490 S1505 S1507 S1509 S1593 T1596 S1607 S1628 T1631 T1660 S1666 S1671 S1674 S1686 T1688 S1690 T1693 S1696 T1878 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S4
S15
S429
S594
S597
Y735
S736
S759
S764
S765
T769
S781
T783
S805
S817
S826
S834
S856
S881
T896
S903
S907
T961
S1042
Y1073
T1075
S1082
S1312
T1378
T1380
T1393
S1396
S1428
S1490
S1505
S1507
S1509
S1593
T1596
S1607
S1628
T1631
T1660
S1666
S1671
S1674
S1686
T1688
S1690
T1693
S1696
T1878
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S4
S15
S429
S594
S597
Y735
S736
S759
S764
S765
T769
S781
T783
S805
S817
S826
S834
S856
S881
T896
S903
S907
T961
S1042
Y1073
T1075
S1082
S1312
T1378
T1380
T1393
S1396
S1428
S1490
S1505
S1507
S1509
S1593
T1596
S1607
S1628
T1631
T1660
S1666
S1671
S1674
S1686
T1688
S1690
T1693
S1696
T1878
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.