PARK7: Parkinsonism associated deglycase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1j42 chain A
1p5f chain A
1pdv chain A
1pdw chain A
1pdw chain B
1pdw chain C
1pdw chain D
1pdw chain E
1pdw chain F
1pdw chain G
1pdw chain H
1pe0 chain A
1pe0 chain B
1q2u chain A
1soa chain A
1ucf chain A
1ucf chain B
2or3 chain A
2or3 chain B
2r1t chain A
2r1t chain B
2r1u chain A
2r1u chain B
2r1v chain A
2r1v chain B
2rk3 chain A
2rk4 chain A
2rk6 chain A
3b36 chain A
3b38 chain A
3b3a chain A
3bwe chain A
3bwe chain B
3bwe chain C
3bwe chain D
3bwe chain E
3bwe chain F
3bwe chain G
3cy6 chain A
3cyf chain A
3cz9 chain A
3cza chain A
3ezg chain A
3f71 chain A
3sf8 chain A
3sf8 chain B
4bte chain A
4mnt chain A
4mtc chain A
4n0m chain A
4n12 chain A
4ogf chain A
4oq4 chain A
4p2g chain A
4p34 chain A
4p35 chain A
4p36 chain A
4rkw chain A
4rky chain A
4s0z chain A
4zgg chain A
5ip5 chain A
5sy6 chain A
5sy9 chain A
5sya chain A
6af5 chain A
6af7 chain A
6af9 chain A
6afa chain A
6afb chain A
6afc chain A
6afd chain A
6afe chain A
6aff chain A
6afg chain A
6afh chain A
6afi chain A
6afj chain A
6afl chain A
6e5z chain A
6m8z chain A
7c62 chain A
7pa2 chain AAA
7pa3 chain AAA
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T19 KGAEEMET VIPVDVM 2 27 - - - - - - - - - - 10 9 4 4 - - - - - - S47 GKDPVQCS RDVVICP 10 877 70 - 99 76 31 40 81 - 35 20 65 61 54 48 32 10 59 26 58 12 S57 VVICPDAS LEDAKKE 6 117 53 - - - 4 5 - - 7 2 15 13 - - 7 2 - - 7 2 Y67 DAKKEGPY DVVVLPG 1 8 - - - - - - - - - - - - 4 4 - - - - - - S85 GAQNLSES AAVKEIL 2 33 - - 5 4 - - - - - - - - - - - - - - 18 6 S161 TSRGPGTS FEFALAI 1 8 - - - - - - 8 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T19 KGAEEMET VIPVDVM - - - - - - - - - - - S47 GKDPVQCS RDVVICP -1.4e-56 - -3.2e-19 -6.8e-10 - -3.5e-8 -1.8e-20 -3.1e-10 -3.6e-3 -3.9e-9 0.86 S57 VVICPDAS LEDAKKE - - - - - - - - - - - Y67 DAKKEGPY DVVVLPG - - - - - - - - - - - S85 GAQNLSES AAVKEIL - - - - - - - - - - - S161 TSRGPGTS FEFALAI - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T19
S47
S57
Y67
S85
S161
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation CCRCC T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation COAD T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation GBM T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation HNSCC T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation LSCC T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation LUAD T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation OV T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation PDAC T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation UCEC T19 S47 S57 Y67 S85 S161 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T19
S47
S57
Y67
S85
S161
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T19
S47
S57
Y67
S85
S161
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.