Protein: ENSP00000340691
Gene: EIF4EBP1

LinkedOmicsKB © 2022-2023 Zhang Lab

EIF4EBP1:
eukaryotic translation initiation factor 4E binding protein 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y34VQLPPGDYSTTPGGT1025526-292010827-36231095471196114
S35QLPPGDYSTTPGGTL713818-87--9-4424202018----6-
T36LPPGDYSTTPGGTLF710832-448189-------6242172
T37PPGDYSTTPGGTLFS1032524-43222272-2313108441132395218
T41YSTTPGGTLFSTTPG8759-88--9-635544--4172
S44TPGGTLFSTTPGGTR8858-545418-116--54--4272
T45PGGTLFSTTPGGTRI912917-8717--17111513543151122
T46GGTLFSTTPGGTRII107066-88647099-6335201744631389368918
S65FLMECRNSPVTKTPP101437122-10380414899-10862108991101017618105449518
T68ECRNSPVTKTPPRDL51349---10818---28271816------
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y34VQLPPGDYSTTPGGT-0.57-0.022---0.002-----
S35QLPPGDYSTTPGGTL0.83-----0.071-0.13---
T36LPPGDYSTTPGGTLF-----------
T37PPGDYSTTPGGTLFS-0.17---0.015--0.034----0.028
T41YSTTPGGTLFSTTPG-----------
S44TPGGTLFSTTPGGTR-----------
T45PGGTLFSTTPGGTRI-----------
T46GGTLFSTTPGGTRII-1.6e-5---1.5e-4--3.5e-80.17--0.055-1.6e-30.015
S65FLMECRNSPVTKTPP0.82-2.7e-17-1.9e-3--6e-70.121-0.032-0.86-0.98
T68ECRNSPVTKTPPRDL-0.53------0.53----
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationCCRCCY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationCOADY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationGBMY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationHNSCCY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationLSCCY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationLUADY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationOVY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationPDACY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylationUCECY34S35T36T37T41S44T45T46S65T68T70T77T82S83S85S86S94S96S101S112proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.