MIA3: MIA SH3 domain ER export factor 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5kyn chain C
5kyu chain C
5kyw chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S186 PEPVEANS EESDSVF 10 433 41 - 9 8 15 12 90 - 49 25 28 27 23 20 14 2 37 14 10 9 S189 VEANSEES DSVFSEN 3 21 - - - - - - - - 6 3 - - - - 3 - - - 7 2 S194 EESDSVFS ENTEDLQ 2 15 - - 8 - - - - - 5 2 - - - - - - - - - - S298 ETTRLVTS LEDDFDE 6 348 - - 73 61 9 9 53 - 79 46 5 5 - - - - - - 5 3 S358 PTDKEQNS NEEDKVQ 1 23 23 - - - - - - - - - - - - - - - - - - - S407 TMDLESSS SEEEKED 10 543 9 - 17 16 53 46 81 - 59 32 20 18 13 11 14 3 38 18 77 18 S408 MDLESSSS EEEKEDD 10 489 9 - 41 22 17 27 46 - 50 30 15 15 14 12 34 6 86 33 18 14 S423 DDALVPDS KQGKPQS 1 18 - - - - - - 18 - - - - - - - - - - - - - S610 GAKLHTLS VEHQREE 2 20 - - 4 4 - - - - - - - - - - - - 9 3 - - S686 EGEAKEDS LDEEFFH 1 64 - - - - - - 64 - - - - - - - - - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S186 PEPVEANS EESDSVF 0.002 - - - - 0.47 0.016 0.032 - 0.35 - S189 VEANSEES DSVFSEN - - - - - - - - - - - S194 EESDSVFS ENTEDLQ - - - - - - - - - - - S298 ETTRLVTS LEDDFDE -3e-7 - -8.9e-9 - - -0.13 - - - - - S358 PTDKEQNS NEEDKVQ - - - - - - - - - - - S407 TMDLESSS SEEEKED -0.69 - - -8.4e-3 - -0.96 0.019 - - -0.15 0.37 S408 MDLESSSS EEEKEDD -0.37 - -0.017 - - 0.005 - - - -0.05 - S423 DDALVPDS KQGKPQS - - - - - - - - - - - S610 GAKLHTLS VEHQREE - - - - - - - - - - - S686 EGEAKEDS LDEEFFH - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S186
S189
S194
S298
S358
S407
S408
S423
S610
S686
Y725
S727
S833
S876
S1419
S1431
S1539
S1553
S1662
S1666
S1670
S1673
S1678
T1682
S1691
S1706
S1717
S1725
S1727
S1731
T1733
T1735
S1739
S1740
S1741
S1744
S1745
S1882
S1884
S1900
S1906
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation CCRCC S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation COAD S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation GBM S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation HNSCC S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation LSCC S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation LUAD S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation OV S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation PDAC S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation UCEC S186 S189 S194 S298 S358 S407 S408 S423 S610 S686 Y725 S727 S833 S876 S1419 S1431 S1539 S1553 S1662 S1666 S1670 S1673 S1678 T1682 S1691 S1706 S1717 S1725 S1727 S1731 T1733 T1735 S1739 S1740 S1741 S1744 S1745 S1882 S1884 S1900 S1906 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S186
S189
S194
S298
S358
S407
S408
S423
S610
S686
Y725
S727
S833
S876
S1419
S1431
S1539
S1553
S1662
S1666
S1670
S1673
S1678
T1682
S1691
S1706
S1717
S1725
S1727
S1731
T1733
T1735
S1739
S1740
S1741
S1744
S1745
S1882
S1884
S1900
S1906
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S186
S189
S194
S298
S358
S407
S408
S423
S610
S686
Y725
S727
S833
S876
S1419
S1431
S1539
S1553
S1662
S1666
S1670
S1673
S1678
T1682
S1691
S1706
S1717
S1725
S1727
S1731
T1733
T1735
S1739
S1740
S1741
S1744
S1745
S1882
S1884
S1900
S1906
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.