RANBP3: RAN binding protein 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2crf chain A
2y8f chain A
2y8f chain B
2y8f chain C
2y8f chain D
2y8g chain A
2y8g chain B
5xzx chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S27 QKDKGQKS PAEQKNL 5 274 28 - - - - - - - - - 53 47 61 56 14 3 7 5 - - S35 PAEQKNLS DSGEEPR 6 217 - - - - - - - - 24 14 25 22 24 20 41 10 5 1 25 6 S72 PPAPAGAS ASTPPPP 1 17 - - - - - - - - 10 7 - - - - - - - - - - T75 PAGASAST PPPPAPE 1 19 - - - - - - 19 - - - - - - - - - - - - - S96 PRELAGRS AGGSSPE 4 92 8 - - - - - - - - - 10 9 - - - - 4 2 54 5 S100 AGRSAGGS SPEGGED 8 1074 113 - 103 80 - - 9 - 108 62 108 99 110 101 - - 105 44 23 9 S101 GRSAGGSS PEGGEDS 8 608 75 - 12 11 - - 72 - 29 17 63 60 52 50 - - 52 22 86 7 S108 SPEGGEDS DREDGNY 8 1161 113 - 103 80 - - 81 - 108 62 98 90 92 84 - - 100 43 89 18 Y115 SDREDGNY CPPVKRE 6 171 - - 4 4 - - - - 7 3 15 14 27 24 - - 32 14 23 4 S125 PVKRERTS SLTQFPP 4 53 - - - - - - 9 - - - 5 5 - - - - 18 7 7 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S27 QKDKGQKS PAEQKNL -0.13 - - - - - -0.12 -0.57 - - - S35 PAEQKNLS DSGEEPR -0.029 - - - - -0.087 -0.48 -4.8e-3 0.38 - - S72 PPAPAGAS ASTPPPP - - - - - - - - - - - T75 PAGASAST PPPPAPE - - - - - - - - - - - S96 PRELAGRS AGGSSPE - - - - - - - - - - - S100 AGRSAGGS SPEGGED 1.6e-18 - -4.6e-11 - - 1e-11 1.4e-14 4.9e-14 - 2.7e-5 - S101 GRSAGGSS PEGGEDS 1.9e-16 - - - - 0.13 3.6e-11 1.4e-9 - 0.024 - S108 SPEGGEDS DREDGNY 0.016 - -5.7e-8 - - 1.8e-4 3.4e-5 2.1e-4 - 0.24 -0.15 Y115 SDREDGNY CPPVKRE 0.079 - - - - - - 0.036 - 0.7 - S125 PVKRERTS SLTQFPP - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S27
S35
S72
T75
S96
S100
S101
S108
Y115
S125
S126
T128
S170
S191
S192
T194
S198
T204
S211
T214
S219
S221
S240
S241
S244
S333
S341
S342
S353
S355
S357
S358
S359
T363
S533
S539
S548
T551
T563
S566
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation CCRCC S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation COAD S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation GBM S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation HNSCC S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation LSCC S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation LUAD S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation OV S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation PDAC S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation UCEC S27 S35 S72 T75 S96 S100 S101 S108 Y115 S125 S126 T128 S170 S191 S192 T194 S198 T204 S211 T214 S219 S221 S240 S241 S244 S333 S341 S342 S353 S355 S357 S358 S359 T363 S533 S539 S548 T551 T563 S566 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S27
S35
S72
T75
S96
S100
S101
S108
Y115
S125
S126
T128
S170
S191
S192
T194
S198
T204
S211
T214
S219
S221
S240
S241
S244
S333
S341
S342
S353
S355
S357
S358
S359
T363
S533
S539
S548
T551
T563
S566
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S27
S35
S72
T75
S96
S100
S101
S108
Y115
S125
S126
T128
S170
S191
S192
T194
S198
T204
S211
T214
S219
S221
S240
S241
S244
S333
S341
S342
S353
S355
S357
S358
S359
T363
S533
S539
S548
T551
T563
S566
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.