ABLIM2: actin binding LIM protein family member 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1v6g chain A
1wig chain A
2l3x chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S17 APSPLEKS PSTAILC 4 227 - - - - - - 99 - 63 34 15 12 - - - - - - 4 - S19 SPLEKSPS TAILCNT 5 132 - - 13 12 - - 27 - 6 4 - - - - - - 42 20 6 2 T20 PLEKSPST AILCNTC 3 33 - - 4 2 - - - - - - 5 5 9 8 - - - - - - S142 SLPVSVGS SAHLSQG 2 46 - - - - - - 36 - 7 3 - - - - - - - - - - T278 DRNKETRT SSESIIS 5 60 - - 4 4 - - - - 12 6 - - 4 4 - - 10 3 11 2 S279 RNKETRTS SESIISV 9 575 - - 38 25 24 21 71 - 84 50 34 31 31 28 27 8 36 13 40 14 S280 NKETRTSS ESIISVP 4 82 - - - - - - 37 - - - 5 4 4 4 - - - - 23 5 S282 ETRTSSES IISVPAS 6 242 - - 35 33 - - 9 - 28 17 49 46 4 5 - - - - 14 2 S285 TSSESIIS VPASSTS 6 123 - - 24 24 - - 9 - 5 3 10 9 17 16 - - 4 2 - - S289 SIISVPAS STSGSPS 1 9 - - - - - - - - 6 3 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S17 APSPLEKS PSTAILC -0.14 - - - - -0.14 - - - - - S19 SPLEKSPS TAILCNT 0.079 - - - - - - - - 0.079 - T20 PLEKSPST AILCNTC - - - - - - - - - - - S142 SLPVSVGS SAHLSQG - - - - - - - - - - - T278 DRNKETRT SSESIIS - - - - - - - - - - - S279 RNKETRTS SESIISV -1.1e-13 - -2.9e-3 0.52 - -1.8e-4 -3.9e-14 -5.4e-5 - 0.21 -1.3e-3 S280 NKETRTSS ESIISVP - - - - - - - - - - - S282 ETRTSSES IISVPAS -1e-10 - -8.1e-7 - - -0.18 -8.7e-7 - - - - S285 TSSESIIS VPASSTS -3.3e-6 - -3.3e-6 - - - - - - - - S289 SIISVPAS STSGSPS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S17
S19
T20
S142
T278
S279
S280
S282
S285
S289
S290
T291
S292
S294
S296
S334
S338
S340
S346
S356
T362
S363
S364
S366
S367
S370
S372
Y376
T377
S382
S391
S396
T397
S399
S404
S446
S452
S461
S462
S476
S487
S488
S502
S512
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation CCRCC S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation COAD S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation GBM S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation HNSCC S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation LSCC S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation LUAD S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation OV S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation PDAC S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation UCEC S17 S19 T20 S142 T278 S279 S280 S282 S285 S289 S290 T291 S292 S294 S296 S334 S338 S340 S346 S356 T362 S363 S364 S366 S367 S370 S372 Y376 T377 S382 S391 S396 T397 S399 S404 S446 S452 S461 S462 S476 S487 S488 S502 S512 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S17
S19
T20
S142
T278
S279
S280
S282
S285
S289
S290
T291
S292
S294
S296
S334
S338
S340
S346
S356
T362
S363
S364
S366
S367
S370
S372
Y376
T377
S382
S391
S396
T397
S399
S404
S446
S452
S461
S462
S476
S487
S488
S502
S512
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S17
S19
T20
S142
T278
S279
S280
S282
S285
S289
S290
T291
S292
S294
S296
S334
S338
S340
S346
S356
T362
S363
S364
S366
S367
S370
S372
Y376
T377
S382
S391
S396
T397
S399
S404
S446
S452
S461
S462
S476
S487
S488
S502
S512
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.