CDK5RAP2: CDK5 regulatory subunit associated protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6x0v chain G
6x0v chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S547 FSKEKKQS SDYEELI 1 6 - - - - - - - - - - - - - - - - 4 2 - - S576 KSLQESDS INNLQAE 4 103 - - 21 10 - - - - - - 20 19 13 11 - - - - 7 2 S697 GFPDRLAS TEQTELL 1 9 - - - - - - - - - - - - - - - - - - 7 2 S725 DDEINFLS DQHLQQS 2 44 - - - - - - - - 12 5 14 13 - - - - - - - - T786 PLFNEKAT LLLESRP 1 8 - - - - - - 8 - - - - - - - - - - - - - T839 ELVHFVQT NSFSKPH 4 113 - - 31 21 - - - - 5 3 20 16 9 8 - - - - - - S841 VHFVQTNS FSKPHDE 3 75 - - - - - - 35 - - - - - - - - - 3 2 33 2 S947 ILIKPSRS LGNMYRL 5 84 - - - - - - 9 - 11 7 - - - - 13 4 3 2 24 11 Y1017 QPPVGAAY QDSPGEQ 1 20 - - - - - - - - - - 10 10 - - - - - - - - S1020 VGAAYQDS PGEQKGI 1 43 - - - - - - - - - - - - - - - - - - 32 11
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S547 FSKEKKQS SDYEELI - - - - - - - - - - - S576 KSLQESDS INNLQAE 0.82 - 0.95 - - - 0.79 - - - - S697 GFPDRLAS TEQTELL - - - - - - - - - - - S725 DDEINFLS DQHLQQS - - - - - - - - - - - T786 PLFNEKAT LLLESRP - - - - - - - - - - - T839 ELVHFVQT NSFSKPH 0.2 - -0.29 - - - 4.4e-3 - - - - S841 VHFVQTNS FSKPHDE - - - - - - - - - - - S947 ILIKPSRS LGNMYRL 6.7e-3 - - - - - - - - - 6.7e-3 Y1017 QPPVGAAY QDSPGEQ - - - - - - - - - - - S1020 VGAAYQDS PGEQKGI 0.04 - - - - - - - - - 0.039
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S547
S576
S697
S725
T786
T839
S841
S947
Y1017
S1020
S1061
S1064
S1074
T1076
S1077
T1080
S1102
S1238
S1350
S1391
S1490
S1666
S1672
T1677
T1684
T1885
S1887
S1889
S1893
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation CCRCC S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation COAD S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation GBM S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation HNSCC S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation LSCC S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation LUAD S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation OV S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation PDAC S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation UCEC S547 S576 S697 S725 T786 T839 S841 S947 Y1017 S1020 S1061 S1064 S1074 T1076 S1077 T1080 S1102 S1238 S1350 S1391 S1490 S1666 S1672 T1677 T1684 T1885 S1887 S1889 S1893 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S547
S576
S697
S725
T786
T839
S841
S947
Y1017
S1020
S1061
S1064
S1074
T1076
S1077
T1080
S1102
S1238
S1350
S1391
S1490
S1666
S1672
T1677
T1684
T1885
S1887
S1889
S1893
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S547
S576
S697
S725
T786
T839
S841
S947
Y1017
S1020
S1061
S1064
S1074
T1076
S1077
T1080
S1102
S1238
S1350
S1391
S1490
S1666
S1672
T1677
T1684
T1885
S1887
S1889
S1893
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.