EPB41: erythrocyte membrane protein band 4.1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1gg3 chain A
1gg3 chain B
1gg3 chain C
2rq1 chain A
3qij chain A
3qij chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S14 LVTEAENS QHQQKEE 5 144 - - - - - - 19 - 10 6 24 23 - - - - 12 4 35 11 S56 CEQKLKAS NGDTPTH 2 37 - - - - - - 10 - - - 14 13 - - - - - - - - T60 LKASNGDT PTHEDLT 4 173 - - - - - - 63 - - - 20 19 8 8 - - - - 50 5 T62 ASNGDTPT HEDLTKN 2 17 - - 4 4 - - - - - - 5 4 - - - - - - - - S84 RGLSRLFS SFLKRPK 2 28 - - - - - - - - - - 5 5 - - - - - - 18 - S85 GLSRLFSS FLKRPKS 7 449 - - 8 7 - - 44 - 63 38 39 36 21 20 - - 79 34 47 13 S92 SFLKRPKS QVSEEEG 7 706 - - 56 39 - - 63 - 74 44 30 29 75 69 - - 94 38 77 18 S95 KRPKSQVS EEEGKEV 7 879 - - 91 69 - - 80 - 85 50 94 86 55 50 - - 87 37 77 18 S104 EEGKEVES DKEKGEG 4 329 - - - - - - 19 - - - 79 72 67 59 - - - - 18 15 T141 APEPELKT DPSLDLH 1 18 - - - - - - - - - - 10 8 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S14 LVTEAENS QHQQKEE 4.3e-5 - - - - - 1.5e-4 - - - 0.046 S56 CEQKLKAS NGDTPTH - - - - - - - - - - - T60 LKASNGDT PTHEDLT 0.011 - - - - - 0.011 - - - - T62 ASNGDTPT HEDLTKN - - - - - - - - - - - S84 RGLSRLFS SFLKRPK - - - - - - - - - - - S85 GLSRLFSS FLKRPKS 0.8 - - - - 4.3e-4 -0.33 -1.2e-3 - 1.1e-4 -1.8e-4 S92 SFLKRPKS QVSEEEG -3.3e-20 - 2.8e-12 - - -1.2e-6 -8e-9 -1.2e-19 - -1.9e-10 -5.0e-4 S95 KRPKSQVS EEEGKEV -8.8e-4 - 1.6e-14 - - -0.86 -1.6e-5 -2.6e-7 - -4.1e-8 -0.48 S104 EEGKEVES DKEKGEG -7.9e-6 - - - - - -0.052 -1.2e-5 - - - T141 APEPELKT DPSLDLH - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S14
S56
T60
T62
S84
S85
S92
S95
S104
T141
S144
S149
S151
S152
T155
S188
S191
Y222
T378
S491
T494
S521
S540
S542
S551
S555
T559
S560
T565
S578
S664
S674
S684
S709
T710
S712
T772
S776
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation CCRCC S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation COAD S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation GBM S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation HNSCC S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation LSCC S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation LUAD S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation OV S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation PDAC S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation UCEC S14 S56 T60 T62 S84 S85 S92 S95 S104 T141 S144 S149 S151 S152 T155 S188 S191 Y222 T378 S491 T494 S521 S540 S542 S551 S555 T559 S560 T565 S578 S664 S674 S684 S709 T710 S712 T772 S776 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S14
S56
T60
T62
S84
S85
S92
S95
S104
T141
S144
S149
S151
S152
T155
S188
S191
Y222
T378
S491
T494
S521
S540
S542
S551
S555
T559
S560
T565
S578
S664
S674
S684
S709
T710
S712
T772
S776
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S14
S56
T60
T62
S84
S85
S92
S95
S104
T141
S144
S149
S151
S152
T155
S188
S191
Y222
T378
S491
T494
S521
S540
S542
S551
S555
T559
S560
T565
S578
S664
S674
S684
S709
T710
S712
T772
S776
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.