RPS3A: ribosomal protein S3A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4ug0 chain SB
4v6x chain AB
5a2q chain B
5aj0 chain BB
5flx chain B
5lks chain SB
5oa3 chain B
5t2c chain Ap
5vyc chain B1
5vyc chain B2
5vyc chain B3
5vyc chain B4
5vyc chain B5
5vyc chain B6
6fec chain i
6g18 chain B
6g4s chain B
6g4w chain B
6g51 chain B
6g53 chain B
6g5h chain B
6g5i chain B
6ip5 chain 2o
6ip6 chain 2o
6ip8 chain 2o
6ole chain SB
6olf chain SB
6olg chain BB
6oli chain SB
6olz chain BB
6om0 chain SB
6om7 chain SB
6qzp chain SB
6xa1 chain SB
6y0g chain SB
6y2l chain SB
6y57 chain SB
6ybd chain O
6ybw chain O
6z6l chain SB
6z6m chain SB
6z6n chain SB
6zlw chain C
6zm7 chain SB
6zme chain SB
6zmi chain SB
6zmo chain SB
6zmt chain C
6zmw chain O
6zn5 chain C
6zoj chain B
6zok chain B
6zon chain p
6zp4 chain p
6zuo chain B
6zv6 chain B
6zvh chain B
6zvj chain p
6zxd chain B
6zxe chain B
6zxf chain B
6zxg chain B
6zxh chain B
7a09 chain p
7k5i chain B
7mq8 chain NM
7mq9 chain NM
7mqa chain NM
7qp6 chain O
7qp7 chain O
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S59 TQGTKIAS DGLKGRV 1 17 - - - - - - - - - - - - - - - - 11 6 - - S154 NNQIRKTS YAQHQQV 6 207 - - - - - - 45 - 54 31 15 13 5 4 - - 21 10 7 2 Y155 NQIRKTSY AQHQQVR 1 9 9 - - - - - - - - - - - - - - - - - - - S236 MELHGEGS SSGKATG 10 906 104 - 57 40 24 38 55 - 73 40 54 50 73 69 40 10 78 33 52 16 S237 ELHGEGSS SGKATGD 8 185 8 - - - 4 5 - - 44 28 15 14 9 9 12 5 13 4 6 9 S238 LHGEGSSS GKATGDE 6 268 8 - - - 47 51 62 - - - - - - - 29 6 12 5 44 4 T242 GSSSGKAT GDETGAK 2 27 - - - - 11 7 9 - - - - - - - - - - - - - S263 YEPPVQES V______ 10 1483 105 - 91 76 97 100 90 - 108 62 98 90 105 97 83 19 105 44 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S59 TQGTKIAS DGLKGRV - - - - - - - - - - - S154 NNQIRKTS YAQHQQV 0.84 - - - - 0.31 - - - -0.47 - Y155 NQIRKTSY AQHQQVR - - - - - - - - - - - S236 MELHGEGS SSGKATG 8.3e-4 - -0.003 0.17 - 9.9e-5 1.5e-4 1.9e-7 0.86 -5e-12 9.9e-7 S237 ELHGEGSS SGKATGD 0.23 - - - - 0.23 - - - - - S238 LHGEGSSS GKATGDE 6.7e-3 - - 6.7e-3 - - - - - - - T242 GSSSGKAT GDETGAK - - - - - - - - - - - S263 YEPPVQES V______ 6.7e-9 - 0.91 6.0e-4 - 3.8e-7 3.7e-17 4.3e-7 -0.043 -4.8e-13 4.0e-4
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S59
S154
Y155
S236
S237
S238
T242
S263
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation CCRCC S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation COAD S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation GBM S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation HNSCC S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation LSCC S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation LUAD S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation OV S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation PDAC S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation UCEC S59 S154 Y155 S236 S237 S238 T242 S263 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S59
S154
Y155
S236
S237
S238
T242
S263
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S59
S154
Y155
S236
S237
S238
T242
S263
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.