Protein: ENSP00000346120
Gene: DDX21

LinkedOmicsKB © 2022-2023 Zhang Lab

DDX21:
DExD-box helicase 21

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S7_MPGKLRSDAGLESD7150--4454--18101091816143--296
S13RSDAGLESDTAMKKG989558-62414842--10862837545422958536659
T15DAGLESDTAMKKGET22717---------55--------
S65VKKKAEPSEVDMNSP45614-44------1513------6-
S71PSEVDMNSPKSKKAK101191121-2020928835-108621089975686215105445415
S74VDMNSPKSKKAKKKE19--54----------------
S84AKKKEEPSQNDISPK35915---------1917------62
S89EPSQNDISPKTKSLR101550122-103789710099-10862108981101018319105449518
S121VTKNEEPSEEEIDAP101542122-103809710099-10258108991101008319105449518
T143EKEMNGETREKSPKL177-------------------
Showing 1 to 10 of 18 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S7_MPGKLRSDAGLESD-----------
S13RSDAGLESDTAMKKG5.9e-47-3.8e-44.2e-21-8e-157.5e-157.1e-3-5.5e-5-
T15DAGLESDTAMKKGET-----------
S65VKKKAEPSEVDMNSP-----------
S71PSEVDMNSPKSKKAK6.4e-34-0.743.1e-23-7.5e-106.5e-328.8e-60.690.320.74
S74VDMNSPKSKKAKKKE-----------
S84AKKKEEPSQNDISPK-----------
S89EPSQNDISPKTKSLR1.2e-86-2.6e-64.7e-31-3.5e-134.4e-351.8e-31-0.691.9e-41.0e-6
S121VTKNEEPSEEEIDAP7.5e-88-1.6e-75.7e-31-2.1e-173.4e-351.6e-324.4e-6-0.0157.3e-6
T143EKEMNGETREKSPKL-----------
Showing 1 to 10 of 18 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationCCRCCS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationCOADS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationGBMS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationHNSCCS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationLSCCS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationLUADS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationOVS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationPDACS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylationUCECS7S13T15S65S71S74S84S89S121T143S147S164S168S171S173S466S513Y721proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.