NFAT5: nuclear factor of activated T cells 5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1imh chain C
1imh chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S17 SADLDLES PKSLYSR 2 80 - - 32 30 - - 18 - - - - - - - - - - - - - S107 SKAMQVES CSSAVGV 4 94 23 - 5 4 - - - - - - 20 18 - - - - - - 17 7 S109 AMQVESCS SAVGVSN 3 47 - - 5 4 - - - - - - 5 4 - - - - - - 25 4 S110 MQVESCSS AVGVSNR 1 7 - - - - - - - - - - - - - - - - - - 7 - S134 NTVQQHPS TPKRHTV 6 141 26 - 3 3 - - - - 29 14 5 4 26 23 6 2 - - - - T135 TVQQHPST PKRHTVL 4 168 15 - - - - - 45 - - - - - - - 59 11 - - 29 9 S145 RHTVLYIS PPPEDLL 3 66 - - - - - - 19 - - - - - - - 33 9 4 1 - - S155 PEDLLDNS RMSCQDE 1 8 - - - - - - - - - - - - - - 5 3 - - - - S220 KRRDCEES NMDIFDA 2 44 - - - - - - - - - - - - 14 12 - - - - 18 - S229 MDIFDADS AKAPHYV 6 393 - - 40 29 - - - - 33 21 49 44 28 24 - - 42 16 54 13
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S17 SADLDLES PKSLYSR -8.3e-4 - -8.3e-4 - - - - - - - - S107 SKAMQVES CSSAVGV 2.6e-3 - - - - - 2.6e-3 - - - - S109 AMQVESCS SAVGVSN - - - - - - - - - - - S110 MQVESCSS AVGVSNR - - - - - - - - - - - S134 NTVQQHPS TPKRHTV 2e-8 - - - - 5.4e-7 - 3.4e-3 - - - T135 TVQQHPST PKRHTVL 0.029 - - - - - - - 0.029 - - S145 RHTVLYIS PPPEDLL - - - - - - - - - - - S155 PEDLLDNS RMSCQDE - - - - - - - - - - - S220 KRRDCEES NMDIFDA - - - - - - - - - - - S229 MDIFDADS AKAPHYV -0.031 - -0.014 - - -0.82 -6.9e-3 -0.042 - -0.035 2.2e-5
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S17
S107
S109
S110
S134
T135
S145
S155
S220
S229
S238
T241
T242
S248
T254
S304
S433
S434
T439
S560
S561
S567
S619
S627
S684
S693
S696
S1014
T1528
S1530
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation CCRCC S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation COAD S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation GBM S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation HNSCC S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation LSCC S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation LUAD S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation OV S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation PDAC S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation UCEC S17 S107 S109 S110 S134 T135 S145 S155 S220 S229 S238 T241 T242 S248 T254 S304 S433 S434 T439 S560 S561 S567 S619 S627 S684 S693 S696 S1014 T1528 S1530 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S17
S107
S109
S110
S134
T135
S145
S155
S220
S229
S238
T241
T242
S248
T254
S304
S433
S434
T439
S560
S561
S567
S619
S627
S684
S693
S696
S1014
T1528
S1530
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S17
S107
S109
S110
S134
T135
S145
S155
S220
S229
S238
T241
T242
S248
T254
S304
S433
S434
T439
S560
S561
S567
S619
S627
S684
S693
S696
S1014
T1528
S1530
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.