HNRNPA2B1: heterogeneous nuclear ribonucleoprotein A2/B1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1x4b chain A
5en1 chain A
5ho4 chain A
5wwe chain A
5wwf chain A
5wwf chain C
5wwg chain A
6wpq chain A
6wqk chain A
6wqk chain B
6wqk chain C
6wqk chain D
6wqk chain E
7wm3 chain A
7wm3 chain B
7wm3 chain C
7wm3 chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T4 ____MEKT LETVPLE 3 84 19 - - - - - - - - - 29 28 4 4 - - - - - - S29 KLFIGGLS FETTEES 9 645 57 - 47 35 - - 98 - 85 49 54 49 69 60 8 1 3 2 17 11 S58 VVMRDPAS KRSRGFG 4 74 - - - - - - - - 5 4 24 22 4 4 - - - - 11 - S71 FGFVTFSS MAEVDAA 6 199 39 - 16 8 5 4 - - - - 35 27 31 28 - - - - 6 - S85 AMAARPHS IDGRVVE 10 1223 52 - 44 35 97 100 98 - 102 59 94 85 78 71 83 19 79 32 77 18 S102 RAVAREES GKPGAHV 10 1240 53 - 103 80 58 67 99 - 104 58 99 90 106 92 7 1 97 41 78 7 T140 EEYGKIDT IEIITDR 2 18 - - - - - - 9 - - - - - - - - - - - 7 2 T145 IDTIEIIT DRQSGKK 1 8 - - - - - - - - - - - - - - 7 1 - - - - S149 EIITDRQS GKKRGFG 9 311 9 - - - 49 41 45 - 11 5 35 34 5 4 19 5 8 3 36 2 T159 KRGFGFVT FDDHDPV 3 83 - - 23 23 - - - - - - - - 13 12 - - - - 12 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T4 ____MEKT LETVPLE -6.5e-4 - - - - - -6.5e-4 - - - - S29 KLFIGGLS FETTEES -0.94 - 0.11 - - -0.1 0.13 -0.11 - - - S58 VVMRDPAS KRSRGFG 5.8e-3 - - - - - 5.8e-3 - - - - S71 FGFVTFSS MAEVDAA 0.14 - - - - - 2.5e-3 -0.34 - - - S85 AMAARPHS IDGRVVE 4.8e-27 - -0.089 1.7e-13 - 0.031 4e-10 8.9e-10 7.6e-6 0.9 1.7e-8 S102 RAVAREES GKPGAHV 2e-34 - -0.047 8.4e-11 - 5.7e-7 4.6e-12 3.8e-18 - 1.2e-6 - T140 EEYGKIDT IEIITDR - - - - - - - - - - - T145 IDTIEIIT DRQSGKK - - - - - - - - - - - S149 EIITDRQS GKKRGFG 1.9e-17 - - 1.5e-8 - - 2.1e-10 - - - - T159 KRGFGFVT FDDHDPV -1 - -1 - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T4
S29
S58
S71
S85
S102
T140
T145
S149
T159
T176
S189
S198
S199
S201
S212
S225
S231
S236
Y244
Y247
S259
S318
S324
Y331
Y336
S341
S344
S351
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation CCRCC T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation COAD T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation GBM T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation HNSCC T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation LSCC T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation LUAD T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation OV T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation PDAC T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation UCEC T4 S29 S58 S71 S85 S102 T140 T145 S149 T159 T176 S189 S198 S199 S201 S212 S225 S231 S236 Y244 Y247 S259 S318 S324 Y331 Y336 S341 S344 S351 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T4
S29
S58
S71
S85
S102
T140
T145
S149
T159
T176
S189
S198
S199
S201
S212
S225
S231
S236
Y244
Y247
S259
S318
S324
Y331
Y336
S341
S344
S351
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T4
S29
S58
S71
S85
S102
T140
T145
S149
T159
T176
S189
S198
S199
S201
S212
S225
S231
S236
Y244
Y247
S259
S318
S324
Y331
Y336
S341
S344
S351
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.