SYNE1: spectrin repeat containing nuclear envelope protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S229 ARENRTDS ACSLKQM 1 27 - - - - - - 27 - - - - - - - - - - - - - S378 PDDEHDLS DRELELE 9 1281 71 - 103 80 93 95 98 - 102 59 100 95 109 101 - - 91 39 34 11 S402 WHDRSADS LLSPQPS 2 17 - - - - - - 9 - - - - - 4 4 - - - - - - S405 RSADSLLS PQPSSNL 9 1082 42 - 103 80 16 19 82 - 96 55 108 99 105 97 - - 84 36 46 14 S409 SLLSPQPS SNLSLSL 2 34 - - 13 12 - - - - - - 5 4 - - - - - - - - S410 LLSPQPSS NLSLSLA 3 32 - - 7 7 - - - - 6 3 - - 5 4 - - - - - - S413 PQPSSNLS LSLAQPL 3 52 - - 4 4 - - - - - - 15 13 8 8 - - - - - - T429 SERSGRDT PASVDSI 8 360 26 - 13 12 6 12 45 - 5 4 48 45 67 60 - - - - 5 12 S432 SGRDTPAS VDSIPLE 9 401 15 - 87 64 21 15 18 - 61 36 10 9 4 4 - - 9 3 29 16 S435 DTPASVDS IPLEWDH 9 466 15 - 25 24 21 15 18 - 51 30 65 59 60 54 - - 9 3 8 9
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S229 ARENRTDS ACSLKQM - - - - - - - - - - - S378 PDDEHDLS DRELELE -9.8e-62 - -0.52 -2e-16 - -1.1e-12 -1e-30 -5.6e-23 - -0.13 -6.3e-7 S402 WHDRSADS LLSPQPS - - - - - - - - - - - S405 RSADSLLS PQPSSNL -1.6e-27 - 0.35 - - -1e-7 -8.4e-31 -4.3e-9 - -0.092 -1.6e-3 S409 SLLSPQPS SNLSLSL - - - - - - - - - - - S410 LLSPQPSS NLSLSLA - - - - - - - - - - - S413 PQPSSNLS LSLAQPL - - - - - - - - - - - T429 SERSGRDT PASVDSI -1e-32 - - - - - -4.3e-20 -1.8e-14 - - - S432 SGRDTPAS VDSIPLE -2.5e-9 - -0.45 -0.45 - -7.8e-8 - - - - -4.9e-7 S435 DTPASVDS IPLEWDH -7.2e-5 - -0.91 -0.45 - -0.14 -1.5e-5 -0.028 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S229
S378
S402
S405
S409
S410
S413
T429
S432
S435
S460
S487
T538
T540
S547
S561
S564
S842
S843
S852
T858
S861
S863
S882
S884
S891
S902
S904
S905
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation CCRCC S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation COAD S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation GBM S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation HNSCC S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation LSCC S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation LUAD S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation OV S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation PDAC S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation UCEC S229 S378 S402 S405 S409 S410 S413 T429 S432 S435 S460 S487 T538 T540 S547 S561 S564 S842 S843 S852 T858 S861 S863 S882 S884 S891 S902 S904 S905 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S229
S378
S402
S405
S409
S410
S413
T429
S432
S435
S460
S487
T538
T540
S547
S561
S564
S842
S843
S852
T858
S861
S863
S882
S884
S891
S902
S904
S905
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S229
S378
S402
S405
S409
S410
S413
T429
S432
S435
S460
S487
T538
T540
S547
S561
S564
S842
S843
S852
T858
S861
S863
S882
S884
S891
S902
S904
S905
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.